Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

Li, Xilin; Le, Yuan; Guo, Xiaoqing; King, Sruthi T.; Dorsam, Robert T.; Atrakchi, Aisar H.; McGovern, Timothy J.; Davis-Bruno, Karen L.; Keire, David A.; Heflich, Robert H.; Mei, Nan

doi:10.1016/j.yrtph.2024.105730

Regulatory Toxicology and Pharmacology

2024

DOI: 10.1016/j.yrtph.2024.105730

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Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

Xilin Li,

Yuan Le,

Xiaoqing Guo

et al.

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Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

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References 33 publications

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