Mutagenic and genotoxic assessment of atrazine-based herbicide to freshwater fish Channa punctatus (Bloch) using micronucleus test and single cell gel electrophoresis

Genotoxic Potential of the Insecticide Imidacloprid in a Non-Target Organism (<i>Oreochromis niloticus</i>-Pisces)

“…The comet assay has been widely used in studies with pesticides; such a test was applied to the fish species Channa punctatus (Channidae) when exposed to atrazine. In this paper, the authors observed an increase in DNA damage in the erythrocytes of these fish [26]. The same results were observed in studies with the phorate pesticide, a genotoxic organophosphate, in fingerlings of Labeo rohita (Cyprinidae) [27], and Roundup ® herbicide, evaluated in Anguilla anguilla (Anguillidae), also displayed genotoxicity [28].…”

Atrazine-Mediated Oxidative Stress Responses and Lipid Peroxidation in the Tissues of Clarias gariepinus

“…Worse hit by chemical pollutants are the fish residents of the aquatic ecosystem and quite a number of studies have reported and confirmed their biological and toxicological responses to atrazine. Some of these include behavioral [6], toxicological and bioavailability [3,7], physiological [4] genetic [8] and biochemical [1,4] responses.…”

Toxicity of Herbicides: Impact on Aquatic and Soil Biota and Human Health

“…Nwani et al [22] evaluated the genotoxic and mutagenic effects of the herbicide Rasayanzine, whose active ingredient is atrazine, using the comet assay and micronucleus test, in erythrocytes and gill cells of the fish Channa punctatus. By the data analysis of the two cell types, significant effects for all the concentrations (4.24, 5.30 and 8.48 mg/L) and exposure periods tested (1, 3, 5, 7, 14, 21, 28 and 35 days) were observed.…”

“…Due to the widespread use of triazine herbicides in the agriculture and, therefore, its high exposure potential for humans, the United States Environmental Protection Agency (USEPA) has conducted a special review on the published and non published data of several triazine herbicides [73]. According to Nwani et al [22], the herbicide atrazine is widely used in crops worldwide. The dangers, both toxic and genotoxic of this herbicide have been revised; however, there is an urgent need for more detailed studies on the mode of action of this compound.…”