Multimedia technology provides a broad space for innovative music education methods and enhancement of learning effects. In order to promote the reform of music teaching in colleges and universities, it is proposed to explore the innovative strategies of music education in colleges and universities under the support of multimedia technology. First of all, the basic characteristics of the conventional college music teaching mode are analyzed, and it is pointed out that the current traditional college music teaching is characterized by authority, protocol and mechanics. Then from the perspective of new media, the current music teaching in colleges and universities is analyzed, including the expansion of learning resources, the transformation of distance learning mode and the promotion of interdisciplinary integration. Finally, specific realization strategies are proposed for music teaching in colleges and universities, including the strengthening of infrastructure construction, the promotion of the transformation of teaching methods and the enhancement of new media teaching cognition. The aim is to utilize the advantages of new media technology to improve the classroom feedback effect of students and cultivate composite music talents.