Mushroom body-specific profiling of gene expression identifies regulators of long-term memory inDrosophila

Abstract

Memory formation is achieved by genetically tightly controlled molecular pathways genes for deficits in long-term memory formation using RNAi knockdown. We identified 10 genes that enhance or decrease memory when knocked-down in the 2 6 mushroom body. For vajk-1 and hacd1, the two strongest hits, we gained further study genes acting at different memory phases.