Musculoskeletal Tuberculosis in Bradford – A 6-Year Review

Talbot, J. Charles; Bismil, Quamar; Saralaya, Dinesh; Newton, Duncan; Frizzel, R M; Shaw, Daigee

doi:10.1308/003588407x183328

Cited by 58 publications

(62 citation statements)

References 18 publications

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“…The majority (74%) of patients was immigrants from the Indian subcontinent. 9 In France, in a hospitalbased survey, the overall incidence of vertebral osteomyelitis was estimated at 2.4/100 000. In 2002-2003, 1422 and 1425 patients were classified as definite (64%), probable (24%), and possible (12%) vertebral osteomyelitis.…”

Section: Epidemiologymentioning

confidence: 99%

Spinal tuberculosis: A review

Garg

Somvanshi

2011

The Journal of Spinal Cord Medicine

623

660

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Spinal tuberculosis is a destructive form of tuberculosis. It accounts for approximately half of all cases of musculoskeletal tuberculosis. Spinal tuberculosis is more common in children and young adults. The incidence of spinal tuberculosis is increasing in developed nations. Genetic susceptibility to spinal tuberculosis has recently been demonstrated. Characteristically, there is destruction of the intervertebral disk space and the adjacent vertebral bodies, collapse of the spinal elements, and anterior wedging leading to kyphosis and gibbus formation. The thoracic region of vertebral column is most frequently affected. Formation of a 'cold' abscess around the lesion is another characteristic feature. The incidence of multi-level noncontiguous vertebral tuberculosis occurs more frequently than previously recognized. Common clinical manifestations include constitutional symptoms, back pain, spinal tenderness, paraplegia, and spinal deformities. For the diagnosis of spinal tuberculosis magnetic resonance imaging is more sensitive imaging technique than x-ray and more specific than computed tomography. Magnetic resonance imaging frequently demonstrates involvement of the vertebral bodies on either side of the disk, disk destruction, cold abscess, vertebral collapse, and presence of vertebral column deformities. Neuroimaging-guided needle biopsy from the affected site in the center of the vertebral body is the gold standard technique for early histopathological diagnosis. Antituberculous treatment remains the cornerstone of treatment. Surgery may be required in selected cases, e.g. large abscess formation, severe kyphosis, an evolving neurological deficit, or lack of response to medical treatment. With early diagnosis and early treatment, prognosis is generally good.

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Section: Epidemiologymentioning

confidence: 99%

Spinal tuberculosis: A review

Garg

Somvanshi

2011

The Journal of Spinal Cord Medicine

623

660

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“…Musculoskeletal TB had been reported from British review study over 6 years, revealing 61 cases (8.4%) out of 729 cases of TB notifications. Of the patients, 74% were immigrants from the Indian subcontinent; nearly 50% had spinal involvement [15]. Another study from Nigeria reported the prevalence of musculoskeletal TB about 0-15% of all TB notification in nonindustrialized world [16].…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

A Case of Multifocal Musculoskeletal Tuberculosis in Pregnant Woman

Albaadani

Anazi

2016

J Med Cases

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“…In the UK, the incidence of TB has risen by 25% over the last 10 years [42]. The resurgence of TB incidence, in developed countries, has been attributed to immigration as well as to a rise in immunosuppressed patients (especially secondary to the HIV epidemic), multidrug-resistant strains of Mycobacterium, an ageing population and increased health-care worker exposure.…”

Section: Tuberculosismentioning

confidence: 99%

“…Extrapulmonary diagnosis remains challenging, and it can be delayed. The musculoskeletal system is involved in 1e3% of patients with TB [42].…”

Section: Tuberculosismentioning

confidence: 99%