DesCripTionAfter a 1-year history of increasing mechanical back pain, a 30-year-old Chadian man with no medical record progressively developed a voluminous paravertebral mass (figure 1A). He described night sweats without fever for several months associated with a 20 kg weight loss (admission weight at 68 kg). Physical examination revealed no neurological defect. Laboratory tests showed a biological inflammatory syndrome with C reactive protein (CRP) plasmatic level at 80 mg/L and fibrinogen at 5.1 g/L.A vertebral MRI showed a T11-T12 vertebral osteomyelitis with a discal and corporeal abscess surrounded by important adjacent bone oedema, epiduritis causing mild spinal cord compression, as well as voluminous, prevertebral (12×8×5 cm), left psoas (9×8×8 cm) and retrovertebral (16×5×4 cm) liquid collections with peripheral contrast enhancement, suggestive of abscesses ( figure 1B-D). Culture of the punctured collection of the retrovertebral abscess yielded multisusceptible Mycobacterium tuberculosis. Body scan revealed no other disease localisation. HIV serological test was negative and CD4 +T cell count (609/mm 3 , 51% of total lymphocytes) was normal. A combination of rifampin (10 mg/kg/d), isoniazid (4.4 mg/kg/d), pyrazinamide (25 mg/kg/d) and ethambutol (20 mg/kg/d) was initiated. Two months later, as the control MRI was strictly stable, the collections were drained, but quickly reconstituted. At that time, drained pus remained sterile in culture. The patients declared a good observance, and drug monitoring showed rifampin, isoniazid, pyrazinamide and ethambutol plasmatic levels within the therapeutic targets. After