Musculoskeletal manifestations of sarcoidosis

Association of histologically proven rheumatoid arthritis with pulmonary sarcoidosis

“…The main pulmonary manifestations of rheumatoid arthritis include pleurisy, with or without effusion, intraparenchymal necrobiotic nodules, Caplan's syndrome, diffuse interstitial pneumonitis with or without fibrosis, obliterative bronchiolitis, pulmonary arteritis and/or hypertension [10]. Musculoskeletal manifestations of sarcoidosis include sarcoid myopathy, osseous osteolytic lesions usually located in hands and feet bones, acute or chronic polyarthritis, usually symmetrical, located on knees, elbows, ankles, wrists and hands, and rarely on sacroiliac joints [11][12][13].…”

Disabling Bilateral Hip Disease and Femoral Bone Defects Revealing Systemic Sarcoidosis

“…Other osseous manifestations are well-defined lytic lesions with sclerotic margins, aggressive-appearing lytic lesions, and, only infrequently, osteosclerosis [3,6]. In our case, it was a moth-eaten osteolysis.…”

An unusual presentation of sarcoidosis with tetraplegia and severe osteolytic bone lesions

“…Mostly, it is only recognised post mortem [1]. Ante mortem, it may be diagnosed radiographically [2] or after lung tumour resection, which is the case in our two patients. These POs can be spread diffusely in the lung, and may be divided into a nodular PO (NPO) and a dendritic PO (DPO), depending on their appearance on CT. Differentiation between DPO and NPO is presented in table 1 [1].…”

“…It is usually a late manifestation and is often associated with chronic pulmonary, cutaneous or multivisceral sarcoidosis. The most common manifestations are asymptomatic lytic lesions of the phalanges of the hands and feet [2]. Involvement of the vertebral column, the skull and the sternum is rare, and virtually all publications are case reports.…”