Musculoskeletal Findings in Behcet's Disease

Abstract

Behcet's disease is a multisystem disease characterized by recurrent oral and genital ulcers, relapsing uveitis, mucocutaneous, articular, gastrointestinal, neurologic, and vascular manifestations. Rheumatologic manifestations may also occur in Behcet's disease, and arthritis and arthralgia are the most common musculoskeletal findings followed by enthesopathy, avascular necrosis, myalgia, and myositis. Although the main pathology of Behcet's disease has been known to be the underlying vasculitis, the etiology and exact pathogenesis of the disease are still unclear. Musculoskeletal findings of Behcet's disease, the relationship between Behcet's disease and spondyloarthropathy disease complex, and the status of bone metabolism in patients with Behcet's disease were discussed in this paper.

Disease Activity in Turkish Patients with Behçet's Disease: Association with Fatigue, Psychological Status and Quality of Life

“…17 Arthritis and arthralgia are the most frequent musculoskeletal findings of BD with a prevalence which varies between 40 and 70%. 2 In our study, the frequency of arthritis was 46.27% and the most common type was asymmetric oligoarthritis (58%).…”

Arthropathy in dermatology: A comprehensive review

“…[52] Patients with arthritis in Behcet's disease predominantly present with recurrent, self-limited, nondeforming, and nonerosive, inflammatory asymmetric mono-oligoarthritis, affecting the larger joints, mainly of the lower limbs. [53] Patients with overlapping features of both relapsing polychondritis and Behcet's disease have been described, and the term MAGIC syndrome (mouth and genital ulcers with inflamed cartilage) has been used for this overlap syndrome. In HSP (now termed IgA vaculitis), ankle and knee joints are most commonly involved and the arthritis is usually nondeforming and self-limiting.…”

Sonographic Evaluation of Subclinical Entheseal Involvement in Patients With Behçet Disease

“…Because radiography and physical examination are not sensitive enough for the detection of early signs of entheseal involvement [1,3], high-resolution ultrasound is widely used as an imaging technique in the diagnosis of enthesopathy [10]. Its sensitivity in the determination of enthesitis has been shown in patients with spondyloarthropathy [8,11,12].…”