Muscone suppresses gastric cancer via regulation of miRNA‐145

Abstract

Muscone is the primary functional component of the natural musk produced by animals such as the musk deer and muskrat. It is usually extracted from the musk sacs or dry exocrine secretions of mature male musk deer (Wang et al., 2020). Some studies have reported that muscone exerts anti-inflammatory effects (Du et al., 2018;He et al., 2020). However, it remains unclear whether muscone exerts antitumor effects in gastric cancer.MicroRNAs (miRNAs) are a class of small, single-stranded, noncoding RNAs that are found widely in eukaryotic cells. miRNAs are 19-25 nucleotides in length and serve important biological functions such as regulating downstream gene transcription by binding to mRNA transcripts of target genes (Hannafon & Ding, 2018).