Muscone ameliorates myocardial ischemia‒reperfusion injury by promoting myocardial glycolysis

Preparation of antioxidant peptides from yak skin gelatin and their protective effect on myocardial ischemia reperfusion injury

“…We performed molecular docking of 10 peptides, which were predicted through online screening, to targets associated with myocardial infarction and reperfusion injury (MI/RI). These targets include tumor necrosis factor-alpha (TNF-α), 38 interleukin-6 (IL-6), 39 kelch-like ECH-associated protein 1 (Keap1), 40 caspase-3 (CASP3), 41 xanthine dehydrogenase (XDH), 42 nitric oxide synthase (NOS), 43 hypoxia-inducible factor-1 alpha (HIF-1α), 44 NADPH oxidase 2 (NOX2), 45 apoptotic protease activating factor-1 (Apaf-1), 46 and others. Fig.…”