Muscle volume is related to trabecular and cortical bone architecture in typically developing children

Bajaj, Deepti; Allerton, Brianne M.; Kirby, Joshua; Miller, Freeman; Rowe, David; Pohlig, Ryan T.; Modlesky, Christopher M.

doi:10.1016/j.bone.2015.07.014

Cited by 13 publications

(6 citation statements)

References 47 publications

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“…Regarding the relationship between BUA and lean body mass, several studies examining factors affecting BUA during adolescence showed results similar to those of this study (Correa-Rodríguez, Rio-Valle, González-Jiménez, & Rueda-Medina, 2016;Zulfarina et al, 2018). Muscle mass in the midthigh has a moderate to strong positive correlation with trabecular bone architecture (Bajaj et al, 2015). According to mechanostat theory, increased muscle mass produces a stimulus for increased bone mass (Rauch, Bailey, Baxter-Jones, Mirwald, & Faulkner, 2004).…”

Section: Discussionsupporting

confidence: 82%

Lifestyle and Environmental Factors Affecting Bone Mass in Japanese Female Adolescents

Okayama

Kinouchi

Watanabe

2021

Journal of Pediatric Nursing

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The subjects were female students aged 15-16 years and their mothers at a public high school in Osaka, Japan. Bone mass was measured using quantitative ultrasound parameters. The body composition was measured using a multi-frequency segmental body composition analyzer. Nutrient intake, exercise habits, and maternal factors as environmental factors were examined using a questionnaire. Results: Logistic regression analyses revealed that the adolescents' lean mass was significantly related to the BUA (p < .05). The adjusted odds ratio was 1.29 (95% confidence interval [CI]: 1.07-1.54). In contrast, the adolescents' exercise habit was significantly related to the SOS (p < .05). The SOS was significantly higher in the adolescents who exercised >4 times a week than in those who exercised <2-3 times a week. The adjusted odds ratio was 2.83 (95% CI: 1.06-7.56). The adolescents' nutrient intake and maternal factors were not significant factors affecting the adolescents' bone mass. Conclusions: The present study suggests that increasing lean mass and exercising more than four times a week were important for increasing bone mass in female adolescents. Practice implications: Nurses should intervene to help female adolescents acquire healthy lifestyle skills and maintain proper body composition and exercise habits to promote bone mass development before reaching PBM.

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Section: Discussionsupporting

confidence: 82%

Lifestyle and Environmental Factors Affecting Bone Mass in Japanese Female Adolescents

Okayama

Kinouchi

Watanabe

2021

Journal of Pediatric Nursing

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“…Thus, higher muscle perimeters are associated with higher calcaneus stiffness. A recent study reported that midthigh muscle volume is moderately-to-strongly related to trabecular bone architecture [ 44 ]. In our study and others, the association between muscle mass and bone parameters is consistent in both sexes [ 45 ].…”

Section: Discussionmentioning

confidence: 99%

Physical Activity, Physical Fitness, Body Composition, and Nutrition Are Associated with Bone Status in University Students

et al. 2018

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Understanding the modifiable factors that improve and maximize peak bone mass at an early age is necessary to design more effective intervention programs to prevent osteoporosis. To identify these modifiable factors, we analyzed the relationship of physical activity (PA), physical fitness, body composition, and dietary intake with bone stiffness index (SI), measured by quantitative ultrasonometry in young university students (18–21 years). Moderate-to-vigorous PA (MVPA) was the strongest predictor of SI (β = 0.184; p = 0.035). SI was most closely related with very vigorous PA in males (β = 0.288; p = 0.040) and with the number of steps/day in females (β = 0.319; p = 0.002). An association between thigh muscle and SI was consistent in both sexes (β = 0.328; p < 0.001). Additionally, extension maximal force was a bone SI predictor factor in females (β = 0.263; p = 0.016) independent of thigh muscle perimeter. Calcium intake was the only nutrition parameter that had a positive relationship with SI (R = 0.217; p = 0.022). However, it was not included as a predictor for SI in our regression models. This study identifies predictors of bone status in each sex and indicates that muscle and bone interrelate with PA and fitness in young adults.

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“…A strong positive-association between bone mass and muscle mass throughout life has been attributed to their shared function (1)(2)(3)(4)(5). This mechano-functional theory has been built upon studies using different approaches.…”

Section: Introductionmentioning

confidence: 99%

Muscle-Bone Crosstalk in the Masticatory System: From Biomechanical to Molecular Interactions

et al. 2021

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The masticatory system is a complex and highly organized group of structures, including craniofacial bones (maxillae and mandible), muscles, teeth, joints, and neurovascular elements. While the musculoskeletal structures of the head and neck are known to have a different embryonic origin, morphology, biomechanical demands, and biochemical characteristics than the trunk and limbs, their particular molecular basis and cell biology have been much less explored. In the last decade, the concept of muscle-bone crosstalk has emerged, comprising both the loads generated during muscle contraction and a biochemical component through soluble molecules. Bone cells embedded in the mineralized tissue respond to the biomechanical input by releasing molecular factors that impact the homeostasis of the attaching skeletal muscle. In the same way, muscle-derived factors act as soluble signals that modulate the remodeling process of the underlying bones. This concept of muscle-bone crosstalk at a molecular level is particularly interesting in the mandible, due to its tight anatomical relationship with one of the biggest and strongest masticatory muscles, the masseter. However, despite the close physical and physiological interaction of both tissues for proper functioning, this topic has been poorly addressed. Here we present one of the most detailed reviews of the literature to date regarding the biomechanical and biochemical interaction between muscles and bones of the masticatory system, both during development and in physiological or pathological remodeling processes. Evidence related to how masticatory function shapes the craniofacial bones is discussed, and a proposal presented that the masticatory muscles and craniofacial bones serve as secretory tissues. We furthermore discuss our current findings of myokines-release from masseter muscle in physiological conditions, during functional adaptation or pathology, and their putative role as bone-modulators in the craniofacial system. Finally, we address the physiological implications of the crosstalk between muscles and bones in the masticatory system, analyzing pathologies or clinical procedures in which the alteration of one of them affects the homeostasis of the other. Unveiling the mechanisms of muscle-bone crosstalk in the masticatory system opens broad possibilities for understanding and treating temporomandibular disorders, which severely impair the quality of life, with a high cost for diagnosis and management.

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Muscle volume is related to trabecular and cortical bone architecture in typically developing children

Cited by 13 publications

References 47 publications

Lifestyle and Environmental Factors Affecting Bone Mass in Japanese Female Adolescents

Lifestyle and Environmental Factors Affecting Bone Mass in Japanese Female Adolescents

Physical Activity, Physical Fitness, Body Composition, and Nutrition Are Associated with Bone Status in University Students

Muscle-Bone Crosstalk in the Masticatory System: From Biomechanical to Molecular Interactions

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