Muscle metaboreflex activation during hypercapnia modifies nonlinear heart rhythm dynamics, increasing the complexity of the sinus node autonomic regulation in humans

Abstract

Author contributions: S.D. conceptualized and designed the study, performed the experiments, processed the data, analyzed the results, wrote the manuscript, and led the research. M.I. gave advice on the study design, performed the experiments, analyzed the results, and discussed and critiqued the manuscript. K.W. gave advice on the experimental setup and performed the experiments. N.F. led the experimental setup, performed the experiments, analyzed the results and discussed the manuscript. T.N. gave advice on the study conception and design as well as the data processing and discussed and challenged the manuscript.