Muscle Invasive Bladder Cancer: From Diagnosis to Survivorship

Mohamed, Nihal; Diefenbach, Michael A.; Goltz, Heather Honoré; Lee, C. T.; Latini, David; Kowalkowski, Marc; Philips, C.S.; Hassan, Waleed; Hall, Simon

doi:10.1155/2012/142135

Cited by 37 publications

(28 citation statements)

References 62 publications

(104 reference statements)

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“…Despite the many studies that compared various urinary reconstructive approaches after RC, there are inadequate data to support the superiority of any of the three urinary diversions in regard to HRQoL 73,78. There are advantages and disadvantages of each procedure; thus, it is of the utmost importance to provide patients with adequate information about each surgical approach to allow individuals to make an informed decision 78.…”

Section: Health-related Quality Of Life For Patients With Bladder Cancermentioning

confidence: 99%

Bladder cancer in the elderly patient: challenges and solutions

Guancial

Roussel

Bergsma

et al. 2015

CIA

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Bladder cancer (BC) is an age-associated malignancy with increased prevalence in the elderly population. Elderly patients are a vulnerable population at increased risk for treatment-related toxicity secondary to medical comorbidities and geriatric syndromes. As a result, this population has been historically undertreated and suffers worse disease-specific outcomes than younger patients with BC. Recognition of this disparity has led to efforts to individualize treatment decisions based on functional status rather than chronologic age in an effort to optimize the use of curative therapies for the fit elderly and modify treatments to reduce the risk of toxicity and disease-related morbidity in vulnerable or frail patients. The comprehensive geriatric assessment is a decision framework that helps to balance underlying health considerations and risks of therapy with aggressiveness of the cancer. Development of systemic therapies with increased efficacy against BC and reduced toxicity are eagerly awaited, as are techniques and interventions to reduce the morbidity from surgery and radiation for patients with BC.

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Section: Health-related Quality Of Life For Patients With Bladder Cancermentioning

confidence: 99%

Bladder cancer in the elderly patient: challenges and solutions

Guancial

Roussel

Bergsma

et al. 2015

CIA

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“…The patients are frequently concerned about odor, urinary leakage and stoma care. Taken together, this can result in social isolation of the patient and hinder them from participating in hobbies and travel activities [24, [27][28][29].…”

Section: Selection Of Patients For Urinary Diversionmentioning

confidence: 99%

“…Studies evaluating quality of life have shown improved body image and sexual function in these patients as compared with those with an ileal conduit [31]. However, the patients must be informed of the need for night time catheterization, since it may lead to sleep disturbance and as such may have an negative impact on quality of life [29].…”

Section: Selection Of Patients For Urinary Diversionmentioning

confidence: 99%

“…There have been many studies comparing different reconstruction procedures after cystectomy [24][25][26][29][30][31][32][33][34][35]; however, the findings have been somewhat varied making it difficult to draw a conclusion on what kind of reconstruction is the best. As there are advantages and disadvantages for each procedure, it must be a joint decision between patient and surgeon.…”

Section: Selection Of Patients For Urinary Diversionmentioning

confidence: 99%

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Strategies to improve quality of life in bladder cancer patients

Roaldsen

Aarsæther

Knutsen

et al. 2014

Expert Review of Pharmacoeconomics & Outcomes Research

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Bladder cancer is a heterogeneous disease that includes both tumors with low risk of dissemination as well as highly malignant tumors with a considerable potential to metastasize. The patient's quality of life is closely related to the management of the disease. The challenge for the urologist is to acknowledge the malignant potential of the cancer and to adjust the approach to the patient accordingly. Patients with low-risk bladder cancer should avoid an exaggerated follow-up, but on the other hand high-risk patients must be sufficiently surveyed to secure that definitive surgical treatment is performed before it's too late. When the decision to perform a cystectomy has been made, it is crucial that the patient understands the consequences of the surgery as well as the possible options for urinary reconstruction. This review focuses on aspects of bladder cancer management that we believe are vital for the quality of life of these patients.

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“…1 With surgical advances and use of neoadjuvant chemotherapy the focus has gone beyond that of cure and disease control to an increasing consideration of HRQoL in this patient group. 2 While ileal conduit and continent cutaneous diversions are old more traditional forms of urinary diversion, orthotopic neobladder reconstruction is a more complex newer diversion type. With regards to the latter, since its introduction neobladder has become increasingly popular.…”

Section: Introductionmentioning

confidence: 99%