Muscle fibre size and myonuclear positioning in trained and aged humans
Edmund Battey,
Yotam Levy,
Ross D. Pollock
et al.
Abstract:Changes in myonuclear architecture and positioning are associated with exercise adaptations and ageing. However, data on the positioning and number of myonuclei following exercise are inconsistent. Additionally, whether myonuclear domains (MNDs; i.e., the theoretical volume of cytoplasm within which a myonucleus is responsible for transcribing DNA) and myonuclear positioning are altered with age remains unclear. The aim of this investigation was to investigate relationships between age and activity status and … Show more
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