Muscle Fiber Diversity and Plasticity

Sänger, Alexandra Maria; Stoiber, Walter

doi:10.1016/s1546-5098(01)18008-8

Cited by 102 publications

(115 citation statements)

References 216 publications

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“…3). The mosaic character of muscle has been suggested to be a result of hyperplastic processes generally only occurring in fish which grow to a large final size (Carpenè and Veggetti 1981;Rowlerson and Veggetti 2001;Sänger and Stoiber 2001;Johnston 2006). The small diameter fibres in the fast muscle of blackspot seabream also differed from the large diameter fibres in their ATPase reactivity (Silva et al 2008).…”

Section: Resultsmentioning

confidence: 99%

Expression of the myosin light chains 1, 2 and 3 in the muscle of blackspot seabream (Pagellus bogaraveo, Brunnich), during development

Silva

Power

Valente

et al. 2010

Fish Physiol Biochem

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Previous studies on the histochemistry and immunoreactivity of fibres in lateral muscle of blackspot seabream indicated that there is a developmental transition in the composition of myofibrillar proteins, which presumably reflects changes in contractile function as the fish grows. We hypothesize that the phenomenon underscores age and spatial differences in the expression of myosin light chains (MLC), not studied yet in this species. In this study, we examined selected stages in the post-hatching development of the muscle of blackspot seabream: hatching (0 days), mouth opening (5 days), weaning (40 days) and juveniles (70 days). The spatial expression of embryonic MLC 1 (MLC1), 2 (MLC2) and 3 (MLC3) was studied by in situ hybridization. Overall, MLC expression patterns were overlapping and restricted to the fast muscle. At hatching and mouth opening, all MLC types were highly expressed throughout the musculature in fast muscle. The expression levels in fast muscle remained high until weaning when germinal zones appeared on the dorsal and ventral areas. The germinal zones were characterized by small-diameter fast fibres with high levels of MLC expression. This pattern persisted up to day 70, when the germinal zones disappeared and expression of MLCs was observed only in the smaller cells of the fast muscle mosaic. These results support our hypothesis and, together with previous imunoand histochemistry results, allow a better understanding of the mechanism of muscle differentiation and growth in fish beyond larval stages, and form-the basis for further comparative and experimental studies with this economically relevant species.

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Section: Resultsmentioning

confidence: 99%

Expression of the myosin light chains 1, 2 and 3 in the muscle of blackspot seabream (Pagellus bogaraveo, Brunnich), during development

Silva

Power

Valente

et al. 2010

Fish Physiol Biochem

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“…The combination of very alkali-stable ATPase, strong reaction with 3/96 (specific for fish fast myosin) and an intermediate staining for SDH is typical of intermediate-pink fibres in many (although not all) fish species (e.g., as reviewed by, Mascarello et al, 1986Mascarello et al, , 1995Sänger and Stoiber, 2001). The strong reaction observed in the intermediate-pink fibres with the antibody for fish fast myosin is in accordance with the recent results obtained in the Steinbacher et al (2006) study.…”

Section: Larvae Aged 0 (Hatching)-40 Daysmentioning

confidence: 99%

“…The mosaic appearance of fast-white muscle is the result of the third hyperplastic process and generally occurs only in fish, which grow to a large final size (Carpenè and Veggetti, 1981;Rowlerson and Veggetti, 2001;Sänger and Stoiber, 2001;Johnston, 2006). In Pagellus bogaraveo small diameter fibres appeared in the fast-white muscle between 70 and 100 days post-hatching, i.e., in early juvenile life, and this was reflected in a wide range of fibre sizes that gave the mosaic appearance in cross sections.…”

Section: Fry Aged 70-100 Daysmentioning

confidence: 99%

“…In Pagellus bogaraveo small diameter fibres appeared in the fast-white muscle between 70 and 100 days post-hatching, i.e., in early juvenile life, and this was reflected in a wide range of fibre sizes that gave the mosaic appearance in cross sections. The ATPase and immunoreactivity profiles of the small diameter fibres in mosaic fast-white muscle vary widely among species (Rowlerson et al, 1985;Romanello et al, 1987;Scapolo et al, 1988;Higgins, 1990;Sänger and Stoiber, 2001). However, in Pagellus bogaraveo we observed the same picture found in Sparus aurata , where the small diameter fibres in the fast-white muscle differed from the large diameter ones only in their ATPase reactivity.…”

Section: Fry Aged 70-100 Daysmentioning

confidence: 99%

“…It is known that developmental transitions in myosin isoform expression are often linked to the formation of distinct 'waves' of fibres, which in fish are the initial embryonic, subsequent stratified and final mosaic phases of myogenesis (e.g., as reviewed by, Rowlerson and Veggetti, 2001;Sänger and Stoiber, 2001;Stellabotte and Devoto, 2007). The primary phase has been well studied in a very few species, most notably Danio rerio (Hamilton) (Devoto et al, 1996(Devoto et al, , 2006Stickney et al, 2000), but the post-embryonic myogenic phases (stratified hyperplasia during larval life, and the later mosaic hyperplasia) have received much less attention.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Muscle differentiation in blackspot seabream (Pagellus bogaraveo, Brunnich): Histochemical and immunohistochemical study of the fibre types

Silva¹,

Rowlerson²,

Valente³

et al. 2008

Tissue and Cell

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The aim of this work was to gain insights into the mechanism of muscle differentiation and growth in Pagellus bogaraveo, by studying muscle fibre phenotypes identified by immunohistochemistry. At hatching, several layers of deep fast-white fibres were covered by a superficial fibre monolayer. At 5 days, slow-red fibres appeared near the lateral line nerve. At 40 days, the intermediate-pink muscle became visible, and in the slow-red and fast-white muscle layers transitions from larval myosin isoforms to the isoforms typical of adult muscle occurred. Between 70 and 100 days, small fibres with a distinct ATPase profile appeared throughout the fast-white muscle, marking the onset of "mosaic" hyperplasia. The myosin of the original superficial monolayer fibres underwent two myosin transformations, before being slowly replaced by an adult slow-red isoform. In juveniles and adults, the slow-red muscle layer could be resolved into two distinct types. The analysis of fibre phenotypes indicated that post-larval muscle growth occurred by two distinct stages of hyperplasia. This study offers a basis for further comparative and experimental studies with this economically relevant species, namely for identifying factors influencing its muscle growth dynamics and disclosing underlying mechanisms.

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Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes

Ono

Kinoshita

Ikeda

et al. 2010

Developmental Dynamics

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We cloned three full-length cDNAs encoding myosin heavy chains (MYHs) previously found to be expressed in embryos or larvae of medaka Oryzias latipes. Based on cDNA sequence information, the three medaka MYH genes, mMYH emb1 , mMYH L1 and mMYH L2 , were localized on the chromosomes. In vivo promoter assay using the gene encoding green or red fluorescent protein and linked to the 5 0 -flanking region of mMYH demonstrated that the transcripts of fast-type mMYH emb1 , first expressed in embryos but belonging to the adult type in phylogenetic analysis, were located in the horizontal myoseptum. On the other hand, embryonic fast-type mMYH L1 and mMYH L2 were expressed in the whole myotomes. Interestingly, cells expressing mMYH emb1 were localized together with engrailed, and cyclopamine, which blocks hedgehog signaling, inhibited mMYH emb1 expression as well as the formation of the horizontal myoseptum, suggesting that muscle pioneer cells express mMYH emb1 as a key protein in the formation of the horizontal myoseptum.

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Muscle Fiber Diversity and Plasticity

Cited by 102 publications

References 216 publications

Expression of the myosin light chains 1, 2 and 3 in the muscle of blackspot seabream (Pagellus bogaraveo, Brunnich), during development

Expression of the myosin light chains 1, 2 and 3 in the muscle of blackspot seabream (Pagellus bogaraveo, Brunnich), during development

Muscle differentiation in blackspot seabream (Pagellus bogaraveo, Brunnich): Histochemical and immunohistochemical study of the fibre types

Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes

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