Muscle fatigue and muscle weakness: what we know and what we wish we did

Karatzaferi, Christina; Chase, P. Bryant

doi:10.3389/fphys.2013.00125

Cited by 10 publications

(4 citation statements)

References 27 publications

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“…Whilst leg muscle or buttock clenching have been recommended for combatting symptomatic OH [12], these manoeuvres may also help conditions where OI is not associated with OH (e.g., postural orthostatic tachycardia syndrome) [13]. The relationship between neuromuscular fatigue and muscular weakness is also known to be heterogeneous [14]. Hypothetically, the experience of general fatigue in an adult with Long Covid could result in the weakening of the 'muscle pump' and hence reduce the PCM-driven rise in blood pressure.…”

Section: Introduction and Healthcare Needmentioning

confidence: 99%

Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid

Duggan¹,

Jennings²,

Monaghan³

et al. 2023

Preprint

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<p>Objective: Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface electromyography (sEMG) and investigated its association with fatigue in adults with Long Covid. Methods: Participants performed an active stand with beat-to-beat hemodynamic monitoring and sEMG of both thighs, including PCM at 3-minutes post-stand. Multivariable linear regression investigated the association between change in systolic blood pressure (SBP) and change in normalised root mean square (RMS) of sEMG amplitude, controlling for confounders including the Chalder Fatigue Scale (CFQ). Results: In 90 participants (mean age 46), mean SBP rise with PCM was 13.7 (SD 9.0) mmHg. In regression, SBP change was significantly, directly associated with change in RMS sEMG (β=0.25, 95% CI 0.07–0.43, P=0.007); however, CFQ was not significant. Discussion/Conclusion: PCM measured by sEMG augmented SBP without the influence of fatigue. </p>

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Section: Introduction and Healthcare Needmentioning

confidence: 99%

Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid

Duggan¹,

Jennings²,

Monaghan³

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…The relationship between neuromuscular fatigue and muscular weakness is also known to be heterogeneous [14]. Hypothetically, the experience of general fatigue in an adult with Long Covid could result in the weakening of the 'muscle pump' and hence reduce the PCM-driven rise in blood pressure.…”

Section: Introduction and Healthcare Needmentioning

confidence: 99%

Characterizing the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults With Long Covid

Duggan

Jennings

Monaghan

et al. 2023

IEEE J. Transl. Eng. Health Med.

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Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface electromyography (sEMG) and investigated its association with fatigue in adults with Long Covid. Participants performed an active stand with beat-to-beat hemodynamic monitoring and sEMG of both thighs, including PCM at 3-minutes post-stand. Multivariable linear regression investigated the association between change in systolic blood pressure (SBP) and change in normalised root mean square (RMS) of sEMG amplitude, controlling for confounders including the Chalder Fatigue Scale (CFQ). In 90 participants (mean age 46), mean SBP rise with PCM was 13.7 (SD 9.0) mmHg. In regression, SBP change was significantly, directly associated with change in RMS sEMG (β = 0.25, 95% CI 0.07-0.43, P = 0.007); however, CFQ was not significant. PCM measured by sEMG augmented SBP without the influence of fatigue.INDEX TERMS Long covid, surface EMG, blood pressure, physical counterpressure manoeuvres, fatigue. Clinical and Translational Impact Statement-The blood pressure-rising effect of physical counterpressure manoeuvres after an active stand can be measured by surface electromyography (sEMG). In adults with Long Covid, this was not influenced by fatigue.

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“…Different fibre types enable muscles to fulfill a variety of functional demands [16], and the endurance ability of the quadriceps femoris has a significant role for functional capabilities during activities of daily living, such as walking and climbing the stairs [17]. Nonetheless, in chronic disease, such as osteoarthritis, muscle fatigue may occur prematurely and persist [18]. The aim of this study is to compare lower limb maximal muscle strength and local muscular endurance in adults with hip osteoarthritis, to an age-matched control group.…”

Section: Introductionmentioning

confidence: 99%

Strength and endurance deficits in adults with moderate-to-severe hip osteoarthritis, compared to healthy, older adults

Burgess

Taylor

Wainwright

et al. 2021

Disability and Rehabilitation

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Purpose: This study compares lower limb muscle strength and endurance in adults with hip osteoarthritis, to an age-matched control group. Methods: Thirteen adults with moderate-to-severe hip osteoarthritis (as graded by the Oxford Hip Score) and fifteen older adults participated.Maximal voluntary isometric contraction of the knee extensors, knee flexors and hip abductors and isotonic endurance of the knee extensors were measured using a dynamometer. Function was assessed using the 30-second chair stand test, the 40 metre fast-paced walk test and a stair negotiation test. Data were compared between groups using t-tests. Results: Participants with hip osteoarthritis demonstrated weakness in the affected limb when compared to the control limb during knee flexion (34%, p=0.004) and hip abduction (46%, p=0.001). Weakness was also observed in the contralateral knee flexors (31%, p=0.01). When compared to the control limb, the knee extensors of the hip osteoarthritis group were exhausted prematurely in the affected (70%, p=0.001) and contralateral limb (62%, p=0.005). The hip osteoarthritis group took twice as long to stair climb (p=0.002), walked 40% slower, (p<0.001) and had a 35% lower sit-stand performance (p<0.001). Conclusions: Moderate-to-severe hip osteoarthritis may be characterised by bilateral deficits in lower-limb maximal strength, markedly lower knee extensor endurance and impaired functional performance.

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Muscle fatigue and muscle weakness: what we know and what we wish we did

Cited by 10 publications

References 27 publications

Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid

Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid

Characterizing the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults With Long Covid

Strength and endurance deficits in adults with moderate-to-severe hip osteoarthritis, compared to healthy, older adults

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