Munchmeyer's disease—a rare case report and review of literature

Sheth, Sachiv; Kumar, S.; Sabhlok, Samrat; Singh, Manju

doi:10.1259/dmfr.20140022

Cited by 7 publications

(5 citation statements)

References 20 publications

(25 reference statements)

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“…Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. [ 3 ] The role of corticosteroids is uncertain and restricted to flare-ups that affect major joints, the jaw, or the submandibular area. Corticosteroids are indicated as the first-line treatment at a brief 4-day course of high-dose corticosteroids, started within the first 24 h of a flare-up, and may help reduce the intense inflammation and tissue edema seen in the early stages of the disease.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 ] It was first described by Patin. [ 3 ] The term FOP is preferred to myositis ossificans because ectopic osteogenesis occurs in the connective tissue within muscles, fasciae, ligaments, tendons, and joint capsules, rather than in the muscle fibers themselves. [ 1 ] In masticatory muscles, however, MOT is a rare condition which was first reported by Ivy and Eby in 1924 affecting the masseter muscle.…”

Section: Introductionmentioning

confidence: 99%

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Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report

Bhansali

Tiwari

Mittal

et al. 2021

Natl J Maxillofac Surg

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Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history and clinicoradiological findings, FOP should be diagnosed as early as possible and noninvasively. The hallmark of diagnosis of FOP is bilateral great toe anomaly present from birth. Misdiagnosis may lead to inadvertent managements, such as manipulations, biopsies, and surgery. Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. FOP may be precipitated due to trauma to muscle. In masticatory muscle, it mainly affects masseter muscle and presents with symptom of trismus. Herein, we present a case of FOP which presented to us with trismus after wooden thorn injury and immobility of the left leg. This article also emphasize on diagnosis, precaution, and treatment of disease.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report

Bhansali

Tiwari

Mittal

et al. 2021

Natl J Maxillofac Surg

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“…In the head and neck region of patients with FOP, heterotopic ossification typically occurs in the masticatory muscles. 4 5 6 7 8 9 This ossification can be triggered by trauma, which may lead to a progressive limitation of mouth opening. Heterotopic ossification is also frequently observed in the nuchal ligaments and adjacent dorsal neck muscles, such as the trapezius muscle.…”

Section: Discussionmentioning

confidence: 99%

Head and neck manifestations of fibrodysplasia ossificans progressiva: Clinical and imaging findings in 2 cases

Kang

Kim

et al. 2023

Imaging Sci Dent

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Fibrodysplasia ossificans progressiva is a rare hereditary disorder characterized by progressive heterotopic ossification in muscle and connective tissue, with few reported cases affecting the head and neck region. Although plain radiographic findings and computed tomography features have been well documented, limited reports exist on magnetic resonance findings. This report presents 2 cases of fibrodysplasia ossificans progressiva, one with limited mouth opening due to heterotopic ossification of the lateral pterygoid muscle and the other with restricted neck movement due to heterotopic ossification of the platysma muscle. Clinical findings of restricted mouth opening or limited neck movement, along with radiological findings of associated heterotopic ossification, should prompt consideration of fibrodysplasia ossificans progressiva in the differential diagnosis. Dentists should be particularly vigilant with patients diagnosed with fibrodysplasia ossificans progressiva to avoid exposure to diagnostic biopsy and invasive dental procedures.

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“…Similar phenomena, of which there have been multiple independent observations, have since had several names, including myositis ossificans progressiva (6), stone man syndrome (7,8), and Münchmeyer's disease (9). These accounts note a predilection for manifesting during childhood or adolescence, with progressive debilitation that begins to affect joints and musculature of the head, neck, and mouth (9) and advancement to fatal involvement and restriction of respiratory structures (10).…”

Section: Introductionmentioning

confidence: 91%