Multiwalled carbon nanotube nanofiller-polyindole polymer matrix-based efficient biosensor for the rapid detection of swine flu

Abstract

The synergistic properties of polyindole (PIN) and multi-walled carbon nanotubes (MTs) are used for the fabrication of efficient biosensing platform towards detection of swine flu using serum amyloid A (SAA)...

3D-phosphorus doped mesoporous graphitic carbon nitride based immunosensor for swine flu detection

“…, glucose (Glu; 70 mg dL −1 ), uric acid (UA; 1 mg mL −1 ), urea (4 mg mL −1 ), lactic acid (LA; 0.5 mM), ascorbic acid (AA; 10 mg mL −1 ), NaCl (9 mg mL −1 ), CaCl 2 (1.13 mM), KCl (8.38 mM), serotonin (Ser; 0.001 μM), Aflatoxin B1 (AfB1; 500 pg mL −1 ), Annexin A2 (Annx II; 10 ng mL −1 ), cardiac troponin I (cTnI; 100 pg mL −1 ), and cytoskeleton-associated protein 4 (CKAP4; 1 ng mL −1 ). 13 As shown in Fig. S6 (ESI†), the occurrence of a drop in I p for the immunosensor after the incorporation of the SAA protein, was due to immunocomplex formation; upon the further addition of analytes, no significant change in I p response was obtained.…”

“…Initially, the DPV response was recorded for the BSA/anti-SAA/ Ser/P-g-C 3 N 4 /ITO bioelectrode against SAA protein (antigen) in analytical solution, and subsequently, a series of interferents including electrolytes and bio-analytes that are present in human blood serum were added to the analytical cell, i.e., glucose (Glu; 70 mg dL À1 ), uric acid (UA; 1 mg mL À1 ), urea (4 mg mL À1 ), lactic acid (LA; 0.5 mM), ascorbic acid (AA; 10 mg mL À1 ), NaCl (9 mg mL À1 ), CaCl 2 (1.13 mM), KCl (8.38 mM), serotonin (Ser; 0.001 mM), Aflatoxin B1 (AfB1; 500 pg mL À1 ), Annexin A2 (Annx II; 10 ng mL À1 ), cardiac troponin I (cTnI; 100 pg mL À1 ), and cytoskeleton-associated protein 4 (CKAP4; 1 ng mL À1 ). 13 As shown in Fig. S6 (ESI †), the occurrence of a drop in I p for the immunosensor after the incorporation of the SAA protein, was due to immunocomplex formation; upon the further addition of analytes, no significant change in I p response was obtained.…”

“…The selection of an immobilization matrix is one of the crucial steps in the development of a biosensor. Various nanomaterials, such as metal oxides, 9,10 metal sulfides, 11 rGO, 12 CNTs, 13 porous carbons, 14 g-C 3 N 4 , 15 etc. , have been used as immobilization matrices for the fabrication of biosensors.…”

“…[6][7][8] The selection of an immobilization matrix is one of the crucial steps in the development of a biosensor. Various nanomaterials, such as metal oxides, 9,10 metal sulfides, 11 rGO, 12 CNTs, 13 porous carbons, 14 g-C 3 N 4 , 15 etc., have been used as immobilization matrices for the fabrication of biosensors. Among them, g-C 3 N 4 has recently attracted interest as an immobilisation matrix for the development of biosensors for the detection of various diseases.…”

Nanostructured zirconia@reduced graphene oxide based ultraefficient nanobiosensing platform for food toxin detection

“…As seen in the the magnitude of the peak currents (both anodic, I pa , and cathodic, I pc ) follows a linear increasing trend against the square root of the scan rate (υ 1/2 ) (inset (i), Fig. 2(c and d)) which signifies that the electrochemical process is diffusion controlled 26,39 and follows eqn (S1) to (S4). † Further, the I pa and I pc values also shift to more positive and negative potentials, respectively, on stepping up the sweep rate.…”