Abstract:The amino acid tryptophan displays emission solvatochromism, an emission maximum that shifts with solvent polarity, which is often used in protein studies to indicate local environment hydrophobicity. Use of tryptophan solvatochromism in time-resolved protein studies has traditionally been complicated due to the undescribed photokinetics that result in a characteristic multiexponential emission decay. For the first time, by application of the photokinetic matrix decomposition (PMD) multivariate curve resolutio… Show more
“…Therefore, the error in the estimate of the actual concentrations can be minimized by using eqn (7) on all predicted concentrations. [52][53][54][55] Occasionally, the predicted content for a particular secondary structure, helical for UVRR and b-sheet for CD, fell below zero. Given that the predicted amounts of secondary structure should be zero or greater, these values were set to zero.…”
Determination of protein secondary structure (α-helical, β-sheet, and disordered motifs) has become an area of great importance in biochemistry and biophysics as protein secondary structure is directly related to protein function and protein related diseases.
“…Therefore, the error in the estimate of the actual concentrations can be minimized by using eqn (7) on all predicted concentrations. [52][53][54][55] Occasionally, the predicted content for a particular secondary structure, helical for UVRR and b-sheet for CD, fell below zero. Given that the predicted amounts of secondary structure should be zero or greater, these values were set to zero.…”
Determination of protein secondary structure (α-helical, β-sheet, and disordered motifs) has become an area of great importance in biochemistry and biophysics as protein secondary structure is directly related to protein function and protein related diseases.
A highly stable MOF, ZJU-108, was synthesized with Zn2+ and 6-(4-pyridyl)-terephthalic acid (H2pta) as construction units, and it exhibits an impressive turn-on luminescence enhancement response to tryptophan.
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