Multisensory Competition Is Modulated by Sensory Pathway Interactions with Fronto-Sensorimotor and Default-Mode Network Regions

Huang, Sai; Li, You; Zhang, Wei; Bao, Zhenan; Liu, Xingzhou; Mo, Lei; Chen, Qi

doi:10.1523/jneurosci.3760-14.2015

Cited by 64 publications

(81 citation statements)

References 40 publications

(6 reference statements)

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“…There are two main types of behavioral outcomes to multisensory integration. The first type are multisensory illusion effects, which involve merging of information across senses; in some cases, one sensory modality within the multisensory information competes for preferential access to the consciousness, which means that this modality dominates the others to receive preferential processing during multisensory competition and eventually dominates the awareness and behavior of the observer (Stein and Meredith, 1993;Driver and Noesselt, 2008;Koelewijn et al, 2010;Talsma et al, 2010;Spence, 2011;Chen and Zhou, 2013;Huang et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Effects of Repetition Suppression on Sound Induced Flash Illusion With Aging

Sun

Liu

et al. 2020

Front. Psychol.

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The sound-induced flash illusion (SiFI) is a classical auditory-dominated multisensory integration phenomenon in which the observer misperceives the number of visual flashes due to the simultaneous presentation of a different number of auditory beeps. Although the SiFI has been documented to correlate with perceptual sensitivity, to date there is no consensus as to how it corresponds to sensitivity with aging. The present study was based on the SiFI paradigm (Shams et al., 2000), adding repeated auditory stimuli prior to the appearance of audiovisual stimuli to investigate the effects of repetition suppression (RS) on the SiFI with aging. The repeated auditory stimuli consisted of one or two of the same auditory stimuli presented twice in succession, which were then followed by the audiovisual stimuli. By comparing the illusions in old and young adults, we aimed to explore the influence of aging on the RS of auditory stimuli on the SiFI. The results showed that both age groups showed SiFI effects, however, the RS performance of the two age groups had different effects on the fusion and fission illusions. The illusion effect in old adults was weaker than in young adults. Specifically, RS only affected fission illusions in the old adults but both fission and fusion illusions in young adults. Thus, the present study indicated that the decreased perceptual sensitivity based on auditory RS could weaken the SiFI effect in multisensory integration and that old adults are more susceptible to RS, showing that old adults perceived the SiFI effect weakly under auditory RS.

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Section: Introductionmentioning

confidence: 99%

Effects of Repetition Suppression on Sound Induced Flash Illusion With Aging

Sun

Liu

et al. 2020

Front. Psychol.

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“…Recent studies show that the modulation of both amplitude and phase of EEG oscillation could be important mechanisms to enable cross-modal interactions [ 7 – 9 ]. In addition, a recent EEG and fMRI study showed that when there is competition between visual and auditory stimuli, requiring active endogenous control of attention, there is modulation of activity within the sensory cortices, sensorimotor areas and the default mode network (DMN) [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Coupling between Theta Oscillations and Cognitive Control Network during Cross-Modal Visual and Auditory Attention: Supramodal vs Modality-Specific Mechanisms

et al. 2016

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Cortical theta band oscillations (4–8 Hz) in EEG signals have been shown to be important for a variety of different cognitive control operations in visual attention paradigms. However the synchronization source of these signals as defined by fMRI BOLD activity and the extent to which theta oscillations play a role in multimodal attention remains unknown. Here we investigated the extent to which cross-modal visual and auditory attention impacts theta oscillations. Using a simultaneous EEG-fMRI paradigm, healthy human participants performed an attentional vigilance task with six cross-modal conditions using naturalistic stimuli. To assess supramodal mechanisms, modulation of theta oscillation amplitude for attention to either visual or auditory stimuli was correlated with BOLD activity by conjunction analysis. Negative correlation was localized to cortical regions associated with the default mode network and positively with ventral premotor areas. Modality-associated attention to visual stimuli was marked by a positive correlation of theta and BOLD activity in fronto-parietal area that was not observed in the auditory condition. A positive correlation of theta and BOLD activity was observed in auditory cortex, while a negative correlation of theta and BOLD activity was observed in visual cortex during auditory attention. The data support a supramodal interaction of theta activity with of DMN function, and modality-associated processes within fronto-parietal networks related to top-down theta related cognitive control in cross-modal visual attention. On the other hand, in sensory cortices there are opposing effects of theta activity during cross-modal auditory attention.

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“…The DMN is involved in affective regulation and internal thoughts (14)(15)(16), showing major changes in psychiatric illnesses, such as BD (17)(18)(19)(20)(21), and major depressive disorder (22)(23)(24). At the same time, the DMN may be related to psychomotor behavior through its relationship with the sensorimotor network (10). Because of the co-occurrence of alterations in affect, thought, and psychomotor behavior in BD, based on existing evidence one could hypothesize abnormal relationships-topographical patterns in the balances between these networks-especially between the DMN and SMN (10) (considering the central clinical role of psychomotor…”

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confidence: 99%

Contrasting variability patterns in the default mode and sensorimotor networks balance in bipolar depression and mania

Martino

Magioncalda

Huang

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

219

141

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Depressive and manic phases in bipolar disorder show opposite constellations of affective, cognitive, and psychomotor symptoms. At a neural level, these may be related to topographical disbalance between large-scale networks, such as the default mode network (DMN) and sensorimotor network (SMN). We investigated topographical patterns of variability in the resting-state signal-measured by fractional SD (fSD) of the BOLD signal-of the DMN and SMN (and other networks) in two frequency bands (Slow5 and Slow4) with their ratio and clinical correlations in depressed (n = 20), manic (n = 20), euthymic (n = 20) patients, and healthy controls (n = 40). After controlling for global signal changes, the topographical balance between the DMN and SMN, specifically in the lowest frequency band, as calculated by the Slow5 fSD DMN/SMN ratio, was significantly increased in depression, whereas the same ratio was significantly decreased in mania. Additionally, Slow5 variability was increased in the DMN and decreased in the SMN in depressed patients, whereas the opposite topographical pattern was observed in mania. Finally, the Slow5 fSD DMN/SMN ratio correlated positively with clinical scores of depressive symptoms and negatively with those of mania. Results were replicated in a smaller independent bipolar disorder sample. We demonstrated topographical abnormalities in frequency-specific resting-state variability in the balance between DMN and SMN with opposing patterns in depression and mania. The Slow5 DMN/SMN ratio was tilted toward the DMN in depression but was shifted toward the SMN in mania. The Slow5 fSD DMN/SMN pattern could constitute a state-biomarker in diagnosis and therapy. bipolar disorder | neuronal variability | default mode network | sensorimotor network B ipolar disorder (BD) type I is a debilitating psychiatric disease with recurrent episodes of depression and mania, characterized by opposite constellations of psychopathological symptoms (1, 2). Typically, depression is characterized by mood biased toward negative affect, cognitive symptoms with thought internally focused: that is, self-focused (which manifests in ruminations) and inhibited psychomotor behavior (which manifests in psychomotor retardation). In contrast, most commonly mania presents mood biased toward positive affect, cognitive symptoms with thought externally focused: that is, environment-focused (which manifests in flight of ideas/ distractibility) and excited psychomotor behavior (which manifests in psychomotor agitation) (1-7). The neural basis underlying such co-occurrence of psychopathological symptoms with opposing constellations in depressive and manic phases of BD, however, remains unclear.Affect, thought, and psychomotor functions can be related to distinct neural networks in the brain's resting state. One central network is the default-mode network (DMN), which was first defined as a group of brain areas consistently showing decrease from baseline state during task-related activity and is indicative of an organization within the brain's ...

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Multisensory Competition Is Modulated by Sensory Pathway Interactions with Fronto-Sensorimotor and Default-Mode Network Regions

Cited by 64 publications

References 40 publications

Effects of Repetition Suppression on Sound Induced Flash Illusion With Aging

Effects of Repetition Suppression on Sound Induced Flash Illusion With Aging

Coupling between Theta Oscillations and Cognitive Control Network during Cross-Modal Visual and Auditory Attention: Supramodal vs Modality-Specific Mechanisms

Contrasting variability patterns in the default mode and sensorimotor networks balance in bipolar depression and mania

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