Multiscale characterization of cortical signatures in positive and negative schizotypy: A worldwide ENIGMA study
Matthias Kirschner,
Benazir Hodzic-Santor,
Leda Kennedy
et al.
Abstract:Positive and negative schizotypy reflect distinct patterns of subclinical traits in the general population associated with neurodevelopmental and schizophrenia-spectrum pathologies. Yet, a comprehensive characterization of the unique and shared neuroanatomical signatures of these schizotypy dimensions is lacking. Leveraging 3D brain MRI data from 2,730 unmedicated healthy individuals, we identified neuroanatomical profiles of positive and negative schizotypy and systematically compared them to disorder-specifi… Show more
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