“…Many special issues in journals [27,34] or reviews have been written on the topic of hybrid modelling in biology, either explicitly or implicitly by focusing on related topics such as multiscale modelling [3,28,43], complexity in biology [9], systems and integrative biology [19,22,23]. Reviews dedicated to some specific applications of hybrid models can also be found, for example in biological networks modelling [12], in cancer modelling [10,21,30,40], and more specifically tumour growth [24,29], tumour immunology [41], brain cancer [42] or angiogenesis [16].…”