In the last years, the internet and multimedia technologies are widely used to exchange medical images and practicing telemedicine; which exposes this data to various illegitimate attacks due to their sensitivity. For this reason, many researchers work to afford a proper security and an efficient protection during the transmission. In this context, we propose a blind multi-watermarking approach for medical images using Lifting Wavelet Transform and Fast Walsh–Hadamard Transform. This approach proves the ability to embed a binary image ([Formula: see text]), used for integrity purposes, in addition to the patient information (EPR) associated with the medical cover image. Moreover, an error correcting code was used to improve the security of the EPR. We tested the proposed approach on different imaging modalities, and the obtained results show a good imperceptibility and robustness against several common attacks.