Multiresistant and blaCTX-M-14-Carrying Salmonella ser. Typhimurium Isolated During a Salmonellosis Outbreak in an Equine Hospital in Argentina

Bustos, C.P.; Dominguez, Johana Elizabeth; Garda, D; Moroni, Mirian; Molinari, Natalia Pallarols; Herrera, Mariana; Chacana, Pablo; Mesplet, María

doi:10.1016/j.jevs.2021.103404

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…Other studies have also reported that S . Typhimurium is the most frequent serotype in equines [ 58 , 63 , 67 , 80 ]. On the contrary, in 2008, the most common serotype among the equines in South Africa was S .…”

Section: Discussionmentioning

confidence: 99%

Occurrence of Salmonella spp. in animal patients and the hospital environment at a veterinary academic hospital in South Africa

Karodia,

Shaik,

Qekwana

2024

Vet World

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Background and Aim: Nosocomial infections caused by Salmonella spp. are common in veterinary facilities. The early identification of high-risk patients and sources of infection is important for mitigating the spread of infections to animal patients and humans. This study investigated the occurrence of Salmonella spp. among patients at a veterinary academic hospital in South Africa. In addition, this study describes the environmental factors that contribute to the spread of Salmonella spp. in the veterinary facility. Materials and Methods: This study used a dataset of Salmonella-positive animals and environmental samples submitted to the bacteriology laboratory between 2012 and 2019. The occurrence of Salmonella isolates at the veterinary hospital was described based on source, month, season, year, and location. Proportions and 95% confidence intervals were calculated for each variable. Results: A total of 715 Salmonella isolates were recorded, of which 67.6% (483/715) came from animals and the remainder (32.4%, 232/715) came from environmental samples. The highest proportion (29.2%) of Salmonella isolates was recorded in 2016 and most isolates were reported in November (17.4%). The winter season had the lowest (14.6%) proportion of isolates reported compared to spring (31.3%), summer (27.8%), and autumn (26.4%). Salmonella Typhimurium (20.0%) was the most frequently reported serotype among the samples tested, followed by Salmonella Anatum (11.2%). Among the positive animal cases, most (86.3%) came from equine clinics. Most reported isolates differed based on animal species with S. Typhimurium being common in equines and S. Anatum in bovines. Conclusion: In this study, S. Typhimurium emerged as the predominant strain in animal and environmental samples. Equines were the most affected animals; however, Salmonella serotypes were also detected in the production animals. Environmental contamination was also a major source of Salmonella species in this study. To reduce the risk of transmission, strict infection prevention and control measures (biosecurity) must be implemented. Keywords: environment, hospital, animals, risk factors, Salmonella enterica, Typhimurium, veterinary.

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Section: Discussionmentioning

confidence: 99%

Occurrence of Salmonella spp. in animal patients and the hospital environment at a veterinary academic hospital in South Africa

Karodia,

Shaik,

Qekwana

2024

Vet World

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“…As a matter of fact, an association between antimicrobial drug treatment and Salmonellosis infection in hospitalised horses has been reported in different studies (Ernst et al, 2004; Hird et al, 1986; House et al, 1999; Kim et al, 2001; Sanchez, 2017). Secondly, the emergence of multidrug‐resistant Salmonella isolates is concerning with regards to nosocomial and zoonotic infections (Bustos et al, 2021; Dor et al, 2020; Leon et al, 2018). Based on this lack of evidence on positive effects, but clear risks for negative effects, one could conclude that there is currently no scientific data supporting the routine use of antimicrobials in adult horses with Salmonellosis.…”

Section: Antibiotic‐associated Diarrhoeamentioning

confidence: 99%

Can the use of antimicrobials in adult equine patients with acute colitis be justified in the era of antimicrobial stewardship?

Durie¹,

Galen

2022

Equine Veterinary Education

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Acute colitis is a potentially life-threatening condition characterised by hypersecretion of fluid, altered motility and an impaired mucosal barrier resulting from direct injury, inflammation and/or dysbacteriosis (Sanchez, 2017). It is responsible for approximately 5% of admissions to equine veterinary hospitals with a mortality of about 40% (Prescott, 2020). Horses with acute colitis present with diarrhoea and potentially other signs such as fever, depression, and colic. It is commonly associated with severe dehydration and electrolyte abnormalities. They can develop SIRS (systemic inflammatory response syndrome) secondary to bacterial translocation, absorption of endotoxin or other bacterial products in the blood stream through a compromised gastrointestinal mucosa (Sanchez, 2017). A variety of infectious and non-infectious aetiologies exist, yet many of the clinical and clinicopathological features are similar regardless of the underlying cause (Sanchez, 2017). In addition, the underlying aetiology remains undetermined in over 50% of the cases (Prescott, 2020). Furthermore, therapeutic principles are similar regardless of the cause and include (1) replacing fluid and electrolyte losses, (2) minimising colonic inflammation and sepsis, (3) promoting mucosal repair and (4) re-establishing normal flora. Some horses require specific therapy aimed at the underlying aetiology (Sanchez, 2017).The routine use of antimicrobials in equine colitis is controversial as antimicrobials may further alter the already compromised normal protective gastrointestinal flora. Additionally, high-level evidence supporting antimicrobial therapy in equine colitis has been previously reported to be lacking (Dunkel & Johns, 2015;Sanchez, 2017).

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In vitro Inhibitory Activity of IgY Antibodies Against Salmonella Ser. Newport Isolated from Horses

Bustos

Leiva

Gambarotta

et al. 2021

Journal of Equine Veterinary Science

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Multiresistant and blaCTX-M-14-Carrying Salmonella ser. Typhimurium Isolated During a Salmonellosis Outbreak in an Equine Hospital in Argentina

Cited by 5 publications

References 21 publications

Occurrence of Salmonella spp. in animal patients and the hospital environment at a veterinary academic hospital in South Africa

Occurrence of Salmonella spp. in animal patients and the hospital environment at a veterinary academic hospital in South Africa

Can the use of antimicrobials in adult equine patients with acute colitis be justified in the era of antimicrobial stewardship?

In vitro Inhibitory Activity of IgY Antibodies Against Salmonella Ser. Newport Isolated from Horses

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