Multireceptor phage cocktail against Salmonella enterica to circumvent phage resistance
Carlos E Martinez-Soto,
Michael McClelland,
Andrew M Kropinski
et al.
Abstract:Non-Typhoidal Salmonella (NTS) is one of the most common foodborne pathogens worldwide, with poultry products being the major vehicle for pathogenesis in humans. The use of bacteriophage (phage) cocktails has recently emerged as a novel approach to enhancing food safety. Here, a multi-receptor Salmonella phage cocktail of five phages was developed and characterized. The cocktail targets four receptors: O-antigen, BtuB, OmpC, and rough Salmonella strains. Structural analysis indicated that all five phages belon… Show more
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