Abstract-This paper presents a synthetic concept on eliminating crosstalk within multiconductor transmission lines (MTLs). Firstly, the method of moments (MoM) is used to calculate the per-unitlength (PUL) parameters of transmission lines. Secondly, the crosstalk is predicted using SPICE circuit simulator. Finally, three methods eliminating crosstalk are used synthetically to design the structure of MTLs. According to the results simulated with software, the effect on eliminating crosstalk by the synthetic design is quite satisfactory. Therefore, the concept may be implimented in practical engineering.