Multiplex Surface-Enhanced Raman Scattering: An Emerging Tool for Multicomponent Detection of Food Contaminants

Abstract

For survival and quality of human life, the search for better ways to ensure food safety is constant. However, food contaminants still threaten human health throughout the food chain. In particular, food systems are often polluted with multiple contaminants simultaneously, which can cause synergistic effects and greatly increase food toxicity. Therefore, the establishment of multiple food contaminant detection methods is significant in food safety control. The surface-enhanced Raman scattering (SERS) technique has emerged as a potent candidate for the detection of multicomponents simultaneously. The current review focuses on the SERS-based strategies in multicomponent detection, including the combination of chromatography methods, chemometrics, and microfluidic engineering with the SERS technique. Furthermore, recent applications of SERS in the detection of multiple foodborne bacteria, pesticides, veterinary drugs, food adulterants, mycotoxins and polycyclic aromatic hydrocarbons are summarized. Finally, challenges and future prospects for the SERS-based detection of multiple food contaminants are discussed to provide research orientation for further.

Determination of Specific Volume Fractions in Multicomponent Liquids Using Hydrogel-Functionalized Plasmonic Sensors

“…Plasmonic sensors generally offer fast on-site detection with compact setups and high sensitivity while giving the possibility of simultaneous data acquisition and multiplexing. These include surfaceenhanced Raman spectroscopy methods [17], [18], optical fiber-based surface plasmon resonance sensors [19]- [21], such as WaveFlex-biosensors [22], [23], and plasmonic sensors utilizing nanostructured sensor surfaces [24], [25]. Each of the systems mentioned above pose promising approaches for the fluid process monitoring.…”

Rapid determination of Ractopamine by SERS coupled with size-tunable Au-Ag alloy

“…Therefore, this study aims to utilize gold-silver alloy substrates in conjunction with SERS technology to achieve rapid detection of ractopamine. By comparing the drawbacks of traditional detection methods with the advantages of SERS technology, as well as the superiority of gold-silver alloy substrates over single gold or silver substrates, we will provide a new, efficient detection method for the field of food safety, contributing to the safeguarding of public health and food safety 7,8 .…”