Multiple Yellow Plaques Assessed by Angioscopy With Quantitative Colorimetry in Patients With Myocardial Infarction

Relationship Between Thin Cap Fibroatheroma Identified by Virtual Histology and Angioscopic Yellow Plaque in Quantitative Analysis With Colorimetry

“…[9][10][11][12][13][14][15] Furthermore, some prospective studies have indicated that the number of yellow plaques in the coronary arteries, or the presence of intense yellow plaques, is a predictor of future cardiac events, such as ACS. 16,17 Therefore, atherosclerotic yellow plaques, especially intense yellow plaques identified by angioscopy, are believed to be vulnerable.…”

“…In this color space, a yellow color intensity can be represented as the b* value (yellow color intensity 0-100, the color of blue -100-0) independent of such conditions as light intensity, the distance from the angioscope's lens to the object, and even the angle of the angioscope to the region of interest. Detailed examinations of L*a*b* color space have been reported previously 13,14 and we used the same colorimetric system. Those reports revealed that a plaque of b* value >23 contains atheroma that has a fibrous cap thickness <100 μm, and that such plaques are more frequently observed in the culprit lesions of ACS than in the culprit lesions of SAP.…”

“…9-13 Furthermore, quantitative evaluation of the yellow plaque could be available with newly developed software using L*a*b* color space. [13][14][15][16] Angioscopic examination of ex vivo human tissue samples has indicated that a coronary plaque with high-intensity, yellow color regions (b*value >23) consists of lipid cores beneath a TCFA (fibrous cap thickness <100 μm). 15 However, there is no available comparison of plaque classification determined by VH-IVUS and by angioscopic findings.…”

What Does the Yellow Color of Angioscopy Mean? Why Yellow Plaque Is Always Vulnerable?

“…Semi-quantitative and Quantitative evaluation of angioscopy All yellow plaques are not a vulnerable, because ACS occurred in a few patients with yellow plaque. [24][25] To detect vulnerable plaque, differentiation of yellow plaque should be needed more accurately and more reliably.…”

Coronary Angioscopic Evaluation for Serial Changes of Luminal Appearance After Pharmacological and Catheter Interventions

“…Furthermore, yellow intensity (or grade) of the plaque is classified semiquantitatively as 0, white; 1, light yellow; 2, (medium) yellow; or 3, dark yellow (Figure 1), or evaluated quantitatively by special software. [8][9][10][11][12][13][14][15][16] The majority of yellow plaques are composed of lipid-rich tissue or necrotic core identified by optical coherence tomography (OCT) and radiofrequency intravascular ultrasound (IVUS). [10][11][12][17][18][19] In contrast, white plaque is histological fibrous plaque or lipid plaque with thick fibrous cap.…”