Multiple Tuberculoma Involving the Brain and Spinal Cord in a Patient with Miliary Pulmonary Tuberculosis

Park, Hyun-Seok; Song, Young‐Jin

doi:10.3340/jkns.2008.44.1.36

Cited by 23 publications

(21 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Imaging modality like CT and MRI scan revolutionized the diagnostic compatibility and exclusion of invasive procedures. As the evolving nature of granuloma showed as low intensity lesions with or without central hyper-intensity on T2 and hypo to iso-intense on T1 weighted images, besides one study showed iso-intense or hypo-intense core with hyper-intense rim on T2 and fluid-attenuated inversion recovery (FLAIR) images as a common presentation but in this study with the most presentation of multiple lesions associated with noncontrast visibility which was ultimately enhanced by the contrast, showed central hyper-intensity on T2 (55%) with meningeal enhancement (80%), FLAIR signals (35%) and hypo-intense core with hyper-intense rim (30%) reflecting the most of cases with early non caseating nature of tuberculoma 7,12,16,19 .…”

Section: Discussionmentioning

confidence: 66%

Tuberculoma Brain and its Early Radiological Presentation; Descriptive Analytical Study

2019

J Liaquat Uni Med Health Sci

View full text Add to dashboard Cite

OBJECTIVE: To highlight the radiological presentation of tuberculoma brain in association with clinical features of the disease METHODOLOGY: As Descriptive analytical nature of study, it was held in Radiology Department of liaquat University Hospital Hyderabad from June 2018 to December 2018. The cases were referred from medicine and neurosurgery ward to the radiology department for MRI and CT scans. The fillings of questionnaire and co relation of its radiological findings with clinical aspect were examined by evaluating patients file and diagnosed on clinical suspicion, CSF findings, improvement on empirical treatment, diagnosis of exclusion and multi discipline discussion. RESULTS: Total numbers of 20 patients were included, mostly younger age were affected with male preponderance. Mostly cases were presented with meningitis (80%), seizures (60%) and history of tuberculosis (60%). On CT and MRI brain scan, the most common findings were multiple lesions (95%) showed central hyper-intensity on T2 (55%) with meningeal enhancement (80%), fluid-attenuate inversion recovery (FLAIR) signals (35%) and hypo-intense core with hyper-intense rim (30%) reflecting the most of cases with early non caseating nature of tuberculoma. Ring like lesions (80%) and irregular shape (45%) with (25%) target like lesions were found and associated with edema (55%) and calcifications (10%). CONCLUSION: The presentation of tuberculoma is no more a rare manifestation of infective CNS disease. Early identification on scans with characteristics of early non caseating granuloma can help in prompt diagnosis and treatment which in turn decreased the disabling nature of disease and its progression.

show abstract

Section: Discussionmentioning

confidence: 66%

Tuberculoma Brain and its Early Radiological Presentation; Descriptive Analytical Study

2019

J Liaquat Uni Med Health Sci

View full text Add to dashboard Cite

show abstract

“…It is classified into pulmonary and extrapulmonary. In this patient, disseminated TB as part of extra-pulmonary TB resulted in tuberculoma of the brain2 in the central nervous system. Tuberculoma of the brain was documented rarely with HIV infection (<1% of extra-pulmonary TB infections with AIDS) 3 4.…”

Section: Discussionmentioning

confidence: 85%

Herpes simplex keratitis-induced endophthalmitis in a patient with AIDS with disseminated tuberculosis

et al. 2014

View full text Add to dashboard Cite

We present the case of a 42-year-old man with AIDS who had lost complete vision of his left eye for the past 15 days. MRI and brightness scan ultrasonography were performed on his eyes that suggested of endophthalmitis with dendritic involvement in the left eye. Viral DNA PCR was performed in aqueous humour sample that confirmed the presence of herpes simplex virus and showed a negative result for cytomegalovirus. The patient was treated with a high dose of oral acyclovir for 10 days and long-term topical acyclovir. Neodymium-doped yttrium aluminum garnet procedure was performed to clear up the cornea, and intraocular pressure was controlled with brimonidine and timolol maleate. The patient was diagnosed to have disseminated tuberculosis (tuberculoma of the brain) and was started with antituberculosis therapy. His condition improved significantly after the treatment, and keratitis in cornea started to clean up.

show abstract

“…Because the patient came with lower limb paralysis and bowel and bladder incontinence, prophylactically screening of the whole spine with sagittal screening of the brain was done. Park and Song 6 have recommended prophylactic cranial imaging in patients with intramedullary spinal cord tuberculoma, so that intracranial tuberculomas can be ruled out. Thacker and Puri 2 reported a case of a young girl who presented with progressive paraparesis, and imaging revealed intramedullary tuberculoma with incidental finding of multiple intracranial tuberculomas.…”

Section: Discussionmentioning

confidence: 99%

Concurrent Pulmonary, Intracranial, Intramedullary Tuberculoma, and Their Response to Conservative Management

Khan¹,

Gupta²,

Jain³

et al. 2018

IJRSMS

View full text Add to dashboard Cite

Tuberculomas of the central nervous system are common. However, the incidence of intraspinal intramedullary tuberculomas is very low, and a combination of intramedullary, intracranial, and pulmonary tuberculomas is extremely rare. We report a case of tuberculoma involving the brain and spine with pulmonary tuberculosis in a 46-year-old man initially presenting with back pain and weakness of both lower extremities. Conservative treatment with antituberculous medications resulted in complete resolution of his symptoms.

show abstract

Multiple Tuberculoma Involving the Brain and Spinal Cord in a Patient with Miliary Pulmonary Tuberculosis

Cited by 23 publications

References 20 publications

Tuberculoma Brain and its Early Radiological Presentation; Descriptive Analytical Study

Tuberculoma Brain and its Early Radiological Presentation; Descriptive Analytical Study

Herpes simplex keratitis-induced endophthalmitis in a patient with AIDS with disseminated tuberculosis

Concurrent Pulmonary, Intracranial, Intramedullary Tuberculoma, and Their Response to Conservative Management

Contact Info

Product

Resources

About