Multiple spontaneous dislocations in a patient with Ehlers-Danlos syndrome

Abstract

Ehlers-Danlos syndrome (EDS) consists of a heterogeneous group of inherited connective tissue disorders, characterised by generalised joint hypermobility, hyperextensibility of the skin, dystrophic scars, and a tendency to excessive bleeding. Sequelae include recurrent low impact trauma dislocations, chronic joint pain, and early osteoarthritis. This report describes a case of multiple simultaneous dislocations at distant sites. We highlight the importance of paying consideration to the exposure of patients to large cumulative doses of ionising radiation to diagnose and confirm reduction of frequent dislocations, and ask whether radiographic confirmation is necessary on every occasion in this subset of patients.

Ehlers–Danlos syndrome: case report and an electron microscopy study

“…The long-term stability or progression and ultimate prognosis are not yet known [4]. In a comparison with other forms of EDS, hypermobility type seems to be the most commonly association with mobility impairment and the most debilitating when compared to musculoskeletal function [9].…”

“…It is less commonly surgical, although historically arthrodesis was common [9]. Surgery may be necessary to correct dislocated joints but it often does not completely resolve the handicap and physical therapy has an important place in management [10].…”

Prolonged varicella viraemia and streptococcal toxic shock syndrome following varicella vaccination of a health care worker

“…Although palmar flexor tenosynovitis is described, 11 acute atraumatic wrist dislocation has not been documented previously as a complication of poststreptococcal reactive arthritis. Occasional reports of atraumatic dislocation of the wrist have been in the setting of a pre‐existing connective tissue disorder or had unknown aetiology 12 , 13 …”

Reconstruction of chronic patellar tendon tear with allograft in a patient with Ehlers-Danlos syndrome

“…The Ehlers‐Danlos syndrome (EDS) is a clinically and genetically heterogeneous connective tissue disorder affecting up to 1 in 5,000 individuals [23]. EDS, a disorder of fibrillar collagen metabolism [3], is characterized in its most common form by hyperextensibility of the skin, hypermobility of joints often resulting in dislocations [7], and tissue fragility exemplified by easy bruising, atrophic scars following superficial injury, and premature rupture of membranes during pregnancy. There is no known cure, and treatment aims to manage the possible complications of the disease.…”