Multiple Spinal Canal Meningiomas

Abstract

BACKGROUND Meningiomas of the spinal canal are common tumours with the incidence of 25 percent of all spinal cord tumours. But multiple spinal canal meningiomas are rare in compare to solitary lesions and account for 2 to 3.5% of all spinal meningiomas. Most of the reported cases are both intra cranial and spinal. Exclusive involvement of the spinal canal by multiple meningiomas are very rare. We could find only sixteen cases in the literature to the best of our knowledge. Exclusive multiple spinal canal meningiomas occurring in the first two decades of life are seldom reported in the literature. We are presenting a case of multiple spinal canal meningiomas in a young patient of 17 years, who was earlier operated for single lesion. We analysed the literature, with illustration of our case.

Multiple ossified spinal meningiomas in the thoracic spine: A case report and literature review

“…The pathogenesis of multiple meningiomas remains elusive. In fact, at present, two kinds of hypotheses are proposed by the relevant literature: one supports the theory of monoclonal spreading and the other suggests that of clonally unrelated onset for lesions arising sequentially from two clearly distinct spinal regions ( 38 ). A genomic profiling study reveals that multiple meningiomas can be of both mono- and multiclonal origin.…”