“…Only a few cases of MSP have been documented in the literature [3,4,5,6]. most of cases reported in the literature of MSP are mainly on vertebral or soft tissue involvement, in our case is very unique for involvement of multiple bone infiltration, mainly of the vault of skull and sternum, costal and humors bilateral , for skull plasmocytoma in the literature they report mainly solitary plasmocytoma ,indeed our case report multiple location of the skull vault and other location , and almost most of the multiple solitary plasmocytoma mimic the metastatic tumor unless confirms the pathological analysis , According to literature search, no case could be found where MSP was associated with skull vault and multiple focal bone infiltration with asymptomatic presentation, although many cases of SBP producing the above features have been reported.…”