Multiple sclerosis in Pakistan

Wasay, Muhammad; Ali, Shahzad; Khatri, Ismail A.; Hassan, Ahmed; Asif, Mohamed Ibrahime; Zakiullah, Nida; Ahmed, Arsalan; Malik, Anjum; Khealani, Bhojo A; Haq, Adnaan; Fredrikson, Sten

doi:10.1177/1352458506072339

Cited by 25 publications

(20 citation statements)

References 3 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although their results are inconsistent with reports from Isfahan and Tehran, it is not surprising because the people who live in this area have different ethnicity and lifestyle compared to people in Isfahan and Tehran. The majority of people in Sistan and Baloochestan are from the Baloch ethnic group, which closely resembles the population residing in Pakistan, where MS is reported to be rare [26,27,28]. Furthermore, nearly half of the population still lives in rural areas, while only 17 and 9% of the population of Isfahan and Tehran, respectively, live in rural areas.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Multiple Sclerosis in Iran: A Systematic Review

Etemadifar¹,

Sajjadi²,

Nasr³

et al. 2013

Eur Neurol

158

105

View full text Add to dashboard Cite

Background: There is a wide variation in the prevalence of multiple sclerosis (MS) in different geographical regions and the epidemiology of MS in Iran has been a major topic of concern during the last decade. Several population-based studies have shown a sharp increase in the prevalence and incidence of MS in this region. In this study, for the first time, the aim was to provide a comprehensive review regarding the incidence and prevalence of MS across Iran. Methods: A comprehensive literature search was performed using PubMed, Embase, and Web of Science. We also did a manual search of reference lists from primary articles and relevant reviews. Databases of ongoing research and unpublished literature were also searched. Results: A total of 22 relevant studies were reviewed and 11 studies met the inclusion criteria. Incidence data were found in 5 studies and ranged from 0.68 to 9.1/100,000 per year in the Iranian population. Prevalence was reported in all studies and ranged from 5.3 to 74.28/100,000 with the higher prevalence among females (female/male ratio ranged from 1.8 to 3.6). The most prevalent subtype of MS was the relapsing-remitting form (65.8-87.8%). The sensory disturbance was the most initial presentation. Conclusion: The incidence and prevalence of MS in Iran has been increasing rapidly, especially in females. Future research should focus on determining the epidemiological features of MS in the neglected provinces with different ethnicities. Such an effort along with further research towards improvement of data on previously studied areas can enable a field to be opened up to identify the patterns of MS in varied genetic backgrounds and environments of Iran.

show abstract

Section: Discussionmentioning

confidence: 99%

Epidemiology of Multiple Sclerosis in Iran: A Systematic Review

Etemadifar¹,

Sajjadi²,

Nasr³

et al. 2013

Eur Neurol

158

105

View full text Add to dashboard Cite

show abstract

“…Meanwhile, the study from Pakistan showed a higher frequency of RIS, despite a lower incidence and prevalence of MS in the region. 23,24,30,31 Gabelic et al 28 showed, in a smaller study in relatives of patients with MS, that 3% fulfilled the RIS criteria by using the DIS-Barkhof criteria, and 10%, with the DIS-Swanton criteria. In healthy volunteers, they found RIS in 2.4% according to the DIS-Barkhof and 3.7% by using DIS-Swanton criteria.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Radiologically Isolated Syndrome: A Population-Based Study

Forslin

Granberg

Jumah

et al. 2016

AJNR Am J Neuroradiol

Self Cite

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE:Incidental MR imaging findings resembling MS in asymptomatic individuals, fulfilling the Okuda criteria, are termed "radiologically isolated syndrome." Those with radiologically isolated syndrome are at high risk of their condition converting to MS. The epidemiology of radiologically isolated syndrome remains largely unknown, and there are no population-based studies, to our knowledge. Our aim was to study the population-based incidence of radiologically isolated syndrome in a high-incidence region for MS and to evaluate the effect on radiologically isolated syndrome incidence when revising the original radiologically isolated syndrome criteria by using the latest radiologic classification for dissemination in space.

show abstract

“…A multicenter hospital database from Karachi, Peshawar and Islamabad among 142 MS patients estimated that the mean age at onset was 27 years, with a female to male ratio of 1.45: 1 [63] .…”

Section: Pakistanmentioning

confidence: 99%

Multiple Sclerosis Epidemiology in East Asia, South East Asia and South Asia: A Systematic Review

Eskandarieh

Heydarpour²,

Minagar³

et al. 2016

Neuroepidemiology

120

View full text Add to dashboard Cite

Background: Multiple sclerosis (MS) is one of the most common chronic immune-mediated diseases of the human central nervous system and an important cause of non-traumatic neurologic disability among young population in several countries. Recent reports from East Asia, South East Asia and South Asia have proposed a low to moderate prevalence of MS in these countries. Methods: A literature review search was carried out in December 2014 in Medline, Embase, Scopus and Cochrane library to recover original population-based studies on MS epidemiology in East Asia, South East Asia and South Asia countries published between January 1, 1950 and December 30, 2014. We intended search strategies using the key words: multiple sclerosis, prevalence, incidence and epidemiology. Based on our inclusion criteria, 68 epidemiologic studies were included in this systematic review. Results: The most extensively used diagnostic criteria in the studies were McDonald's criteria. Most studies were performed in a multi-center hospital setting. The female to male ratio varied and ranged from 0.7 in India to 9.0 in China. The mean age at disease onset ranged from the lowest age of 25.3 in Iran to the highest age of 46.4 in China. MS prevalence ranged from 0.77 in 100,000 populations in Hong Kong (1999) to 85.80 in 100,000 in Iran (2013). Conclusions: Advances in MS registries around the globe allow nationwide population-based studies and will allow worldly comparisons between the prevalence and incidence in different regions that are provided to monitor estimation.

show abstract

Multiple sclerosis in Pakistan

Cited by 25 publications

References 3 publications

Epidemiology of Multiple Sclerosis in Iran: A Systematic Review

Epidemiology of Multiple Sclerosis in Iran: A Systematic Review

Incidence of Radiologically Isolated Syndrome: A Population-Based Study

Multiple Sclerosis Epidemiology in East Asia, South East Asia and South Asia: A Systematic Review

Contact Info

Product

Resources

About