Multiple sclerosis, dental caries and fillings: a case-control study

Abstract

There was evidence of excess dental caries among MS cases compared with the controls. This finding supports the strong geographical correlation between the two diseases. A further study of this association is recommended.

Dental Amalgam and Multiple Sclerosis: A Systematic Review and Meta‐Analysis

“…Four observational studies that met our inclusion criteria (Table 1) (9, 12), three case‐control (9, 11, 12) studies, and one cohort (10) study were found. The studies differ in methodologic qualities mainly in the manner by which MS was diagnosed.…”

“…In 1978 Craelius (7) reported a correlation between multiple sclerosis (MS) and dental caries, and in 1986 Ingalls (8) suggested that this correlation was due to the mercury in dental fillings and proposed its possible role in the etiology of MS. Several observational studies have shown an association between MS and dental amalgam fillings. While Bangsi et al (9), Bates et al (10), and Cassetta et al (11) reported elevated relative risk (RR) for MS and amalgam fillings, McGrother et al (12) found no such correlation. Presented with these discrepant results, we sought to explore and quantify the association between amalgam restorations and MS by conducting a systematic review and meta‐analysis of the literature.…”

Oral health status of a population with multiple sclerosis

“…When this was compared with a group from the general population in their country, significant differences were not found in DMFT index. McGrother et al (6) found a DMFT index of 19.46 in the sample they analyzed, and significant differences were found regarding the control group of healthy individuals. …”

Lead poisoning from complementary and alternative medicine in multiple sclerosis

“…Lead is not associated with the pathogenesis of multiple sclerosis5 6; however, lead poisoning can mimic many diseases. Our study indicates that lead poisoning is a possible differential diagnosis for exacerbation of the symptoms of multiple sclerosis, in particular the cerebellar and cognitive features.…”