Multiple sclerosis affects the frequency content in the vertical ground reaction forces during walking

Wurdeman, Shane R.; Huisinga, Jessie M.; Filipi, Mary L.; Stergiou, Nicholas

doi:10.1016/j.clinbiomech.2010.09.021

Cited by 36 publications

(37 citation statements)

References 19 publications

(35 reference statements)

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“…2, 13 Additionally, biomechanical assessment of kinematic gait parameters in PwMS reveals significant changes in lower extremity movement and force production. 20, 57 The causes of such gait dysfunction are complex and incompletely understood. Factors contributing to mobility disorders in MS may include slowed spinal somatosensory conduction 4 , abnormal sensorimotor control 10 , and leg power asymmetry 9 , among others.…”

Section: Introductionmentioning

confidence: 99%

Accelerometry Reveals Differences in Gait Variability Between Patients with Multiple Sclerosis and Healthy Controls

et al. 2012

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Variability of movement reflects important information for the maintenance of the health of the system. For pathological populations, changes in variability during gait signal the presence of abnormal motor control strategies. For persons with multiple sclerosis (PwMS), extensive gait problems have been reported including changes in gait variability. While previous studies have focused on footfall variability, the present study used accelerometers on the trunk to measure variability during walking. Thus, the purpose of this study was to examine the variability of the acceleration pattern of the upper and lower trunk in PwMS compared to healthy controls. We extracted linear and nonlinear measures of gait variability from 30s of steady state walking for 15 PwMS and 15 age-matched healthy controls. PwMS had altered variability compared to controls with greater Lyapunov exponent in the ML (p < 0.001) and AP (p < 0.001) directions, and greater frequency dispersion in the ML direction (p = 0.034). PwMS also demonstrated greater mean velocity in the ML direction (p = 0.045) and lower root mean square of acceleration in the AP direction (p = 0.040). These findings indicate that PwMS have altered structure of variability of the trunk during gait compared to healthy controls and agree with previous findings related to changes in gait variability in PwMS.

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Section: Introductionmentioning

confidence: 99%

Accelerometry Reveals Differences in Gait Variability Between Patients with Multiple Sclerosis and Healthy Controls

et al. 2012

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“…The value of a sophisticated gait laboratory or dynamic posturography in assessing even mild impairments [9–12] or effect of medications and rehabilitation interventions [13–17] on gait and balance is well-established. However, gait laboratories and dynamic posturography systems are expensive, require large dedicated spaces, dedicated personnel, proper installation and professional interpretation.…”

Section: Need For Better Balance and Gait Assessments In Rehabilitationmentioning

confidence: 99%

Mobility Lab to Assess Balance and Gait with Synchronized Body-worn Sensors

Mancini

King

Salarian

et al. 2013

J Bioengineer & Biomedical Sci

141

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This paper is a commentary to introduce how rehabilitation professionals can use a new, body-worn sensor system to obtain objective measures of balance and gait. Current assessments of balance and gait in clinical rehabilitation are largely limited to subjective scales, simple stop-watch measures, or complex, expensive machines not practical or largely available. Although accelerometers and gyroscopes have been shown to accurately quantify many aspects of gait and balance kinematics, only recently a comprehensive, portable system has become available for clinicians. By measuring body motion during tests that clinicians are already performing, such as the Timed Up and Go test (TUG) and the Clinical Test of Sensory Integration for Balance (CITSIB), the additional time for assessment is minimal. By providing instant analysis of balance and gait and comparing a patient’s performance to age-matched control values, therapists receive an objective, sensitive screening profile of balance and gait strategies. This motion screening profile can be used to identify mild abnormalities not obvious with traditional clinical testing, measure small changes due to rehabilitation, and design customized rehabilitation programs for each individual’s specific balance and gait deficits.

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“…Gait deficits are reported in 80% of persons with MS (PwMS) (Souza et al, 2010), and fall risk is significantly increased with at least 50% of PwMS reporting at least one fall in a 2–6 month period (Nilsagard et al, 2009). Previous gait analysis studies have identified kinetic and kinematic differences in the gait of PwMS compared to healthy control subjects including reduced walking speed and stride length (Benedetti et al, 1999), decreased ankle and knee angular excursions (Gehlsen et al, 1986), altered trunk sway variability (Huisinga et al, 2013), altered step length and step width variability (Kaipust et al, 2012), and lower frequencies in vertical ground reaction forces (Wurdeman et al, 2011). These altered gait parameters in PwMS are influenced by decreased somatosensation (Cattaneo and Jonsdottir, 2009), altered sensorimotor responses (Huisinga et al, 2014), muscle asymmetry (Chung et al, 2008), and spasticity (Pau et al, 2015), and lead to altered gait stability and increased fall risk (Cameron et al, 2008; Huisinga et al, 2014; Nilsagard et al, 2009; Sosnoff et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…Because PwMS have altered sensorimotor responses (Cameron et al, 2008; Huisinga et al, 2014) and many differences in spatial and temporal gait parameters compared to healthy controls (Benedetti et al, 1999; Gehlsen et al, 1986; Huisinga et al, 2013; Kaipust et al, 2012; Wurdeman et al, 2011), we hypothesized that (i) PwMS would exhibit different amounts and different structure of variability for foot and trunk accelerations during walking compared to healthy controls, and (ii) the strength of relationships between variability of accelerations at the foot and at the trunk during walking would be different in PwMS compared to healthy controls.…”

Section: Introductionmentioning

confidence: 99%

The relationship between trunk and foot acceleration variability during walking shows minor changes in persons with multiple sclerosis

Craig

Bruetsch

Lynch

et al. 2017

Clinical Biomechanics

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Background Identifying how relationships between variability of upper and lower body segments during walking are altered in persons with multiple sclerosis may uncover specific strategies for maintaining overall stability. The purpose of this study was to examine relationships between trunk and foot acceleration variability during walking in healthy controls and in persons with multiple sclerosis. Methods Linear and nonlinear variability measures were calculated for 40 healthy controls and 40 persons with multiple sclerosis from the acceleration time series recorded by inertial sensors attached to the trunk and foot while subjects walked on a treadmill at self-selected preferred pace. Findings No main effect of group was found for any variability measures. Main effect of location was found for all variability measures, with larger magnitudes of variability at the foot compared to the trunk, and more predictable variability patterns at the foot compared to the trunk. Differences in strength of correlations between trunk and foot accelerations were found between persons with multiple sclerosis and healthy controls in the frontal and sagittal plane. Sample entropy of accelerations at the feet and at the trunk correlated significantly higher in healthy controls than in persons with multiple sclerosis. Interpretation Relationships between variability of trunk and foot accelerations, which may provide a valuable comprehensive description of whole body stability during gait, showed minor changes in persons with MS compared to healthy controls.

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Multiple sclerosis affects the frequency content in the vertical ground reaction forces during walking

Cited by 36 publications

References 19 publications

Accelerometry Reveals Differences in Gait Variability Between Patients with Multiple Sclerosis and Healthy Controls

Accelerometry Reveals Differences in Gait Variability Between Patients with Multiple Sclerosis and Healthy Controls

Mobility Lab to Assess Balance and Gait with Synchronized Body-worn Sensors

The relationship between trunk and foot acceleration variability during walking shows minor changes in persons with multiple sclerosis

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