Multiple pulmonary microemboli complicating pneumonectomy

Satur, Christopher M.R.; Robertson, Ross; Costa, Philip E. Da; Saunders, Nigel R.; Walker, Duncan R.

doi:10.1016/0003-4975(91)91432-u

Cited by 12 publications

(1 citation statement)

References 14 publications

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“…Therefore, in the context of lung surgery, we postulate that the presence of human heparin in both the pulmonary and systemic circulations (during the intra and post-operative periods) may provide an understanding of the reported reduced incidence of thrombo-embolic complications among thoracic surgical patients. Pulmonary embolism is widely recognized to complicate abdominal and lower limb orthopaedic surgical procedures, but in comparison, it is seldom recognized to hamper the postoperative progress of patients after thoracic operations [15,16]. This low prevalence of pulmonary embolism among thoracic surgical patients was cited by other reports to be 0.7, 1.85, and 3.1% [17 -19].…”

Section: Discussionmentioning

confidence: 94%

Intra-operative heparin release during lung surgery☆

Ashour

Hajjar

Alkattan

et al. 2004

European Journal of Cardio-Thoracic Surgery

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Within the context of lung surgery for carcinoma or inflammatory diseases, it appears that operative trauma enhances heparin release into both the pulmonary and systemic circulations, possibly through pulmonary mast cell degranulation. Thus, an episodic auto anti-coagulant effect is established during the course of surgery. Such findings may partly provide an understanding of the excessive bleeding encountered during some thoracotomies and the recognized reduced incidence of thrombo-embolic complications among thoracic surgical patients. Should an unexplained bleeding occur during the course of surgery, an excess of heparin release is recommended to be kept in mind as a possible cause.

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Section: Discussionmentioning

confidence: 94%