Multiple organ segmentation framework for brain metastasis radiotherapy

Yu, Hui; Yang, Ziyuan; Zhang, Zhongzhou; Wang, Tao; Ran, Maoson; Wang, Zhiwen; Liu, Lunxin; Liu, Yan; Zhang, Yi

doi:10.1016/j.compbiomed.2024.108637

Computers in Biology and Medicine

2024

DOI: 10.1016/j.compbiomed.2024.108637

|View full text |Cite

Multiple organ segmentation framework for brain metastasis radiotherapy

Hui Yu,

Ziyuan Yang,

Zhongzhou Zhang

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

FLASH Radiotherapy: Mechanisms of Biological Effects and the Therapeutic Potential in Cancer

Yan,

Wang,

Wang

et al. 2024

Biomolecules

View full text Add to dashboard Cite

Radiotherapy is an important treatment for many unresectable advanced malignant tumors, and radiotherapy-associated inflammatory reactions to radiation and other toxic side effects are significant reasons which reduce the quality of life and survival of patients. FLASH-radiotherapy (FLASH-RT), a prominent topic in recent radiation therapy research, is an ultra-high dose rate treatment known for significantly reducing therapy time while effectively targeting tumors. This approach minimizes radiation side effects on at-risk organs and maximally protects surrounding healthy tissues. Despite decades of preclinical exploration and some notable achievements, the mechanisms behind FLASH effects remain debated. Standardization is still required for the type of FLASH-RT rays and dose patterns. This review addresses the current state of FLASH-RT research, summarizing the biological mechanisms behind the FLASH effect. Additionally, it examines the impact of FLASH-RT on immune cells, cytokines, and the tumor immune microenvironment. Lastly, this review will discuss beam characteristics, potential clinical applications, and the relevance and applicability of FLASH-RT in treating advanced cancers.

show abstract

FLASH Radiotherapy: Mechanisms of Biological Effects and the Therapeutic Potential in Cancer

Yan,

Wang,

Wang

et al. 2024

Biomolecules

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Multiple organ segmentation framework for brain metastasis radiotherapy

Cited by 1 publication

References 33 publications

FLASH Radiotherapy: Mechanisms of Biological Effects and the Therapeutic Potential in Cancer

FLASH Radiotherapy: Mechanisms of Biological Effects and the Therapeutic Potential in Cancer

Contact Info

Product

Resources

About