“…The pathogenesis of the familial incidence of myelomatosis has partially been ex plained by the demonstration of abnor malities of the karyotype [5,6,13,14,16,22,23,25],…”
The distribution of phenotypes and gene frequencies of the group-specific component (Gc) and haptoglobin (Hp) were studied in 169 and 177 patients with multiple myeloma, respectively. The statistical analysis of our findings in comparison to the frequency of these genes in the general population does not support any correlation between the distribution of these phenotypes and the multiple myeloma or its immunological classes.
“…The pathogenesis of the familial incidence of myelomatosis has partially been ex plained by the demonstration of abnor malities of the karyotype [5,6,13,14,16,22,23,25],…”
The distribution of phenotypes and gene frequencies of the group-specific component (Gc) and haptoglobin (Hp) were studied in 169 and 177 patients with multiple myeloma, respectively. The statistical analysis of our findings in comparison to the frequency of these genes in the general population does not support any correlation between the distribution of these phenotypes and the multiple myeloma or its immunological classes.
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