Multiple Myeloma in a Patient with Hoarseness, Dysphagia, Aspiration, and Cervical Lymphadenopathy

Abstract

A bst ract Mu ltipl e niyeloma , which primarily aifeets the elderly, is rare in the head and ne ck. We report the ease oja 7J-yearold man who came to IIS with hoarseness , dysphagia, int ermittent aspiration, and cervieal lymphadenopathy. Our work-up included laboratory tests, radiographic examinations, ana lysi s ofbone tnarrow aspiration, and histopathologic evaluatio ns. Cervi cal lymph node biopsy confirmed a diagnosis ofmultiple myel oma. Despite treatm ent with chemotherapy and radiation, the patient died of his disease 6 months later.

Fine‐needle aspiration cytology for the diagnosis of plasma cell neoplasms in the head and neck region: A systematic analysis of the literature

“…The electronic searches yielded 1143 articles (PubMed: 418, Web of Science: 292, Embase: 265, and Scopus: 168) and 82 studies reporting 102 individuals were included in this systematic review 17–98 (Figure 1).…”

“…Most cases were primary and extraosseous lesions. However, both extraosseous and intraosseous lesions result in a variety of findings, including swelling associated or not with pain, facial asymmetry, numbness, paraesthesia, and hoarseness 17–98 . Notably, the findings indicated that most cases had a diagnosis of plasmacytoma (extramedullary or solitary of bone) and the remaining ones had systemic involvement by PCM.…”

“…A recent systematic review identified concordance rates higher than 64% for the smear and 77% for the cell‐block technique regarding diagnostic capability for the evaluation of intraosseous jaw lesions, including malignant lesions 16 . Despite several published reports on the cytopathological diagnosis of PCN, either in isolated manifestations (extramedullary or solitary bone plasmacytoma) or as a consequence of PCM, 17–98 there is a lack of compiled information investigating the agreement of cytopathological and histopathological findings, along with others ancillary cytological methods such as smears and cell blocks. In fact, FNAC represents a faster, cheaper and more diversified noninvasive diagnostic approach.…”

Multiple Myeloma: An Unexpected Cause of Dysphagia After Cervical Spine Surgery

“…However, most orthopedic surgeons are unfamiliar with this procedure and remain confused with its safety, which might lead to misdiagnosis in the current setting. Furthermore, a few cases of MM with the presentation of dysphagia have been reported [ 7 , 8 ]. However, MM presenting as dysphagia after cervical spine surgery is rarely reported.…”