1992
DOI: 10.1148/radiology.182.3.1535904
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Multiple myeloma: appearance at MR imaging.

Abstract: Magnetic resonance (MR) imaging examinations of the lumbar spine and clinical and laboratory findings in 32 patients with multiple myeloma were reviewed. On T1-weighted images, signal intensity (SI) of the vertebrae approximated that of muscle in 14 cases and was intermediate (between the SIs of muscle and fat) in 18. Definite foci of decreased SI were seen in eight cases (25%), and foci of increased SI, representing fatty infiltration, were seen in 12 (38%). On T2-weighted images, SI approximated that of musc… Show more

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Cited by 112 publications
(35 citation statements)
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“…Solitary plasmacytoma of the bone was known to have a similar signal intensity to muscle on T1-weighted images and spinal multiple myeloma is of similar or higher signal intensity to muscle signal intensity (2,3). The difference in signal intensity between our study and previous studies could be a attributed to improved tissue contrast of the MR imaging.…”
Section: Discussionsupporting
confidence: 40%
“…Solitary plasmacytoma of the bone was known to have a similar signal intensity to muscle on T1-weighted images and spinal multiple myeloma is of similar or higher signal intensity to muscle signal intensity (2,3). The difference in signal intensity between our study and previous studies could be a attributed to improved tissue contrast of the MR imaging.…”
Section: Discussionsupporting
confidence: 40%
“…Infiltration of the bone marrow by myeloma has been described previously as broad categories of focal, patchy/variegated, or diffuse infiltration. [16][17][18][19][20][21][22] The current study describes a semiquantitative way to assess bone marrow infiltration by MRI that may be more reproducible.…”
Section: Discussionmentioning
confidence: 99%
“…Among the MR imaging patterns of multiple myeloma infiltration, the focal involvement pattern may mimic atypical VHs [35][36][37][38]. Changes between pre-and post-treatment MR images, in terms of dimension and signal intensity, help to differentiate multiple myeloma from atypical VHs [39] (Fig.…”
Section: Atypical Vhsmentioning
confidence: 99%