Multiple malignant epithelioid mesotheliomas of the liver and greater omentum: a case report and review of the literature

Abstract

BackgroundMalignant mesothelioma commonly arises from the pleura, but can also arise from the peritoneum, pericardium, and tunica vaginalis testis. However, malignant mesothelioma of the liver is extremely rare and coexistence with malignant mesothelioma of the greater omentum has not been described in the literature. In this case report, we present a case of multiple malignant mesothelioma of the liver and greater omentum.Case presentationA 36-year-old woman was admitted to our hospital for the evaluation of an elastic hard mass in the right upper abdomen. Abdominal contrast computed tomography showed a cystic mass measuring 13 × 14 × 11 cm in the right liver lobe with enhanced mural nodule. Abnormal accumulation was identified in the liver and lower abdominal area on 18F-fluorodeoxyglucose positron emission tomography. The patient underwent hepatectomy of the posterior segment and partial resection of the omentum. The final pathological diagnosis was low-grade multiple malignant epithelioid mesothelioma based on characteristic immunohistochemical findings. As of 6 months postoperatively, the patient has shown no disease recurrence.ConclusionsWe present the first case of a 36-year-old woman with multiple malignant mesothelioma of the liver and greater omentum.

Incidental finding of diffuse malignant greater omentum mesothelioma during lung tumor diagnosis

“…[2] However, malignant omental mesothelioma is exceptionally unusual and to our knowledge there are only a few cases described in English literature. [3] The occurrence of mesothelioma is commonly associated with asbestos exposure, which is still the most significant risk factor for this disease.…”