Multiple Liver Metastases of a Neuroendocrine Carcinoma of Unknown Origin

Morihiro, Toshiaki; Aoki, Hideki; Kanaya, Nobuhiko; Takeda, Sho; Sui, Kenta; Shigeyasu, Kunitoshi; Arata, Toshiaki; Koh, Katsuyoshi; Tanakaya, Koji; Takeuchi, Hitoshi

doi:10.5833/jjgs.2014.0022

Cited by 1 publication

(3 citation statements)

References 12 publications

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“…The tumor (red arrows) near the esophagus (yellow arrows) has remarkably decreased in size and it has almost completely disappeared. (2,3). In this patient, a mediastinal tumor was the only lesion that could be clinically identified.…”

Section: Discussionmentioning

confidence: 69%

“…No primary origin of NEN is found in approximately 11-22% of patients with NEN, and such cases are designated as NENs of UPO ( 5 ). NENs of UPO are often found as multiple liver and lymph node metastases or peritoneal dissemination ( 1 ), and have a poorer prognosis compared to metastatic NENs with a known primary site ( 2 , 3 ).…”

Section: Discussionmentioning

confidence: 99%

“…NEC of unknown primary origin (UPO) is rare and often found in liver or lymph nodes (1). Generally, its prognosis is extremely poor with a rapid increase and early systemic metastases (2,3). We herein report a case of NEC of UPO which was difficult to distinguish from a recurrence of esophageal squamous carcinoma which had been resected 8 years previously.…”

Section: Introductionmentioning

confidence: 96%

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Mediastinal Neuroendocrine Carcinoma Slowly Growing for 8 Years after Surgical Resection of Esophageal Squamous Cell Carcinoma

et al. 2020

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A 70-year-old woman was referred to our department due to a solitary mediastinal tumor which gradually grew near the site of anastomosis for 8 years after radical surgery of esophageal squamous cell carcinoma. It was difficult to distinguish the lymph node recurrence of esophageal cancer from another tumor of unknown primary origin. Endoscopic ultrasound-guided fine-needle aspiration was performed, and the tumor was diagnosed to be neuroendocrine carcinoma. She received concurrent chemoradiotherapy with etoposide plus cisplatin. After the completion of chemoradiotherapy, the tumor disappeared. A solitary growing tumor which develops after radical resection of cancer would be better to be examined histologically in order to make an accurate diagnosis and select the most appropriate treatment.

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Section: Discussionmentioning

confidence: 69%