Multiple linear bowenoid papulosis without surrounding papules

Bowenoid papulosis in a linear distribution

“…Bowenoid papulosis was characterized by slightly elevated papules or plaques in the genital region that histologically resembled Bowen's disease (BD) [ 1 ]. Its lesions may be discrete or coalesce to form patches, rings to a rare linear patterns [ 2 ].…”

“…The surfaces of the lesion mostly are flat, dome-shaped, papillomatous and verrucous. Bowenoid papulosis's colors are highly variable, they can be shiny flesh-colored, pink, reddish-brown, black, violaceous or may show coloration similar to that of the surrounding skin or mucosa [ 1 , 2 ]. Most lesions of BP were described to be discrete, albeit some had an annular or linear exhibition.…”

“…To the best of our knowledge, no more than 5 cases of LBP had been reported in the English literature prior to this [ 2 , 4 – 7 ]. We found this subtype has following distinctive clinical features: 1) the lesions are intermittent or consecutive, linear configuration; 2) these linear lesions were distributed in a direction that is almost exclusively vertical with the shaft of the penis; 3) males are more susceptible than females (5 males out of 6 cases); 4) coronary sulcus and adjacent areas are the predominant sites of involvement.…”

“…Bowenoid papulosis, BD and erythroplasia of Queyrat are distinct clinical entities with similar histological findings of intraepithelial neoplasia. Bowenoid papulosis may show acrotrichial sparing, less pronounced cellular dysplasia and mitotic figures, which helps its differentiation [ 1 , 2 ]. Another histological differentiation of BP is Podophyllin treated condyloma accuminatum, which can be easily excluded by medical history of the patients.…”

“…Most cases of BP are due to high-risk human papillomavirus 16 (HPV-16), but in a small number, HPV-18, 31, 33, 35, 39, and 53, or mixed infections, have been present [ 2 , 8 ]. Some specialists advocate that LBP is a direct result of Koebner phenomenon [ 4 ] through direct contact or autoinoculation of these pathogens.…”