Multiple keratoacanthomas possibly induced by psoralens and ultraviolet A photochemotherapy

The histologic spectrum of epithelial neoplasms induced by sorafenib

“…11,12 Iatrogenic causes include topical photodynamic therapy with 5-aminolevulinic acid, imiquimod, cyclosporine, suramin, psoralen plus ultraviolet A photochemotherapy, ultraviolet B phototherapy, Cook body peel, and polychemotherapy. [13][14][15][16][17][18][19][20][21] The epithelial invaginations in our patient demonstrated a range of keratinocyte atypia, including an AK in his right forearm lesion and an invasive SCC with KA-like architecture on his right shoulder. Both the AK and KA-like SCC bore clinical resemblance to other lesions in our patient.…”

Keratoacanthoma as a postoperative complication of skin cancer excision

“…14 There are reports of KAs that developed in patients receiving psoralen-UVA treatment and radiation therapy. 7,8,15,16 In 1997, Hamilton et al 5 reported a case of KA developing in a split-skin graft donor site of a patient with a burn injury. Recently, a case of multiple KAs after carbon-dioxide laser resurfacing has been reported.…”

Generalized Eruptive Keratoacanthoma of Grzybowski: Follow-Up of the Original Description and 50-Year Retrospect

“…The patient of Grzybowski remained immunocompetent during the follow-up, as were most other patients with eruptive KAs, although some authors reported an association with immunosuppression [26, 27, 28]or onset after PUVA therapy for psoriasis [29]and radiotherapy [30]. The interesting possibility is the role of professional hazards [5, 31].…”