“…Missing data for adjustment variables were imputed by means of a multiple imputation procedure. 20 We explored potential interactions between use of menopausal hormone therapy and covariates by including an interaction term in the models.…”
“…Missing data for adjustment variables were imputed by means of a multiple imputation procedure. 20 We explored potential interactions between use of menopausal hormone therapy and covariates by including an interaction term in the models.…”
“…Recruitment rates varied by center and this may introduce selection bias; however, previous analysis suggests little bias for most of the age range [38]. Fractures outcomes were based on self-reported fractures, and this implies potential mechanisms of additional ascertainment bias provided there were between-center differences in fracture questionnaire response rates.…”
Background-Striking geographic variation in the incidence of osteoporotic fracture has been shown in national and international studies. The contributing risk factors for this variation are not fully understood.
“…Multiple imputation was initially considered and would have merit for correcting at least some of the bias [21,22]. However, it was not utilized since it too has limitations within the context of non-ignorable data.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citationsâcitations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.