Multiple idiopathic cervical root resorption: A systematic review

Abstract

The current literature on multiple idiopathic cervical root resorption (MICRR), a rare and aggressive form of external root resorption, is limited to case reports and series. Therefore, we performed a systematic review of this condition. A comprehensive search of PubMed, Embase, Web of science, Cochrane Library, CNKI, and WANFANG was conducted using key terms relevant to MICRR, supplemented by a grey literature search. Risk of bias was assessed using Cochrane's and Joanna Briggs Institute's tools. A total of 36 studies with 47 cases were included. MICRR is more common among younger females and may be related to hormonal changes and denosumab use. Initially, the premolars are usually affected but all permanent teeth may eventually be involved. Cone‐beam computed tomography is recommended for diagnosis and assessment of resorptive lesions. The management is focused on complete removal and restoration of the resorptive tissue to maintain the tooth's structural integrity. However, MICRR usually has a poor prognosis. Due to its invasive and aggressive behavior, MICRR requires greater attention.

Surgical repair of external cervical resorption - Prognosis and prognostic factors

“… 2 , 4 , 5 Conversely, the etiology of ECR in MEAT is more obscured and could be related to some generalized factors, such as thyroid or parathyroid disorders, 4 , 20 , 21 autoimmune disease, 22 elevated alkaline phosphatase, 23 drug-induced and rebound effects after cessation of anti-resorptive treatment, 24 viral infections, inherited genetic variants, and hormonal changes. 24 , 25 Probably an underlying problem is kept stimulating the development of ECR, contributing to its high recurrent potential.…”

Crosstalk between stomatology and medical genetics: Viewpoints of Chinese scholars

“…This special issue comprises nine invited reviews from OGDRD committee members, focusing on congenital dental abnormalities such as hereditary enamel and dentin defects (Dong et al, 2023; Su et al, 2023; Yuan et al, 2023; Zhang et al, 2023), tooth agenesis (Lan et al, 2022), multiple idiopathic cervical root resorption (Wang et al, 2022), craniofacial and oral malformations including non‐syndromic skeletal Class III malocclusion (Zhou et al, 2022), mandibular coronoid process hyperplasia (Wang, 2022), and hemifacial microsomia (Luo et al, 2023).…”

“…Meanwhile, Lan et al (2022) described the syndromes associated with tooth agenesis, including monogenic diseases with mutations in almost 20 genes and several chromosomal anomalies (Lan et al, 2022). Furthermore, Wang et al (2022) comprehensively described 20 systemic diseases or syndromes associated with coronoid process hyperplasia (Wang, 2022). These findings emphasize the importance for dental clinicians to recognize that dental or craniofacial phenotypes may serve as indicators of systemic diseases.…”

“…This special issue also delves into the diagnosis, differential diagnosis, and treatment approaches for several diseases. Wang et al (2022) conducted a systematic review focusing on multiple idiopathic cervical root resorption, providing the diagnostic strategies and treatment options for this condition (Wang et al, 2022). In the case of hemifacial microsomia, Luo et al (2023) introduced the OMENS‐Plus classification system to enhance the accuracy of diagnosis and optimize treatment approaches (Luo et al, 2023).…”

“…The first section of this special issue focuses on the complex phenotypes associated with oral genetic diseases. These abnormalities can specifically affect the teeth, craniofacial bones, and (Wang et al, 2022). In the case of hemifacial microsomia, Luo et al (2023) introduced the OMENS-Plus classification system to enhance the accuracy of diagnosis and optimize treatment approaches (Luo et al, 2023).…”