Multiple HPV infections among men who have sex with men engaged in anal cancer screening in Abuja, Nigeria

Nowak, Rebecca G.; Schumaker, Lisa M.; Ambulos, Nicholas P.; Ndembi, Nicaise; Dauda, Wuese; Nnaji, Chinedu H; Mitchell, Andrew; Mathias, Trevor J.; Jibrin, Paul; Darragh, Teresa M.; Olaomi, Oluwole; Crowell, Trevor A; Baral, Stefan; Charurat, Manhattan; Bentzen, Søren M.; Palefsky, Joel M.; Cullen, Kevin J.

doi:10.1016/j.pvr.2020.100200

Cited by 12 publications

(22 citation statements)

References 45 publications

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“…Lowe et al (2012) 11 Medina-Laabes et al (2018) 12 Machalek et al (2016) 13 Hernandez et al (2013) 14 Gaisa et al (2021) 15 de Pokomandy et al (2009) 16 Clarke et al (2018) 17 Wilkin et al (2018) 18 Viciana et al (2019) 19 Phanuphak et al (2013) 20 Combes et al (2018) 21 Sambursky et al (2018) 22 Fuchs et al (2016) 23 Burgos et al (2015) 24 Posada et al (2020) 25 Nowak et al (2020) 26…”

Section: Hra For All Participantsmentioning

confidence: 99%

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

et al. 2021

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Background Robust age-specific estimates of anal human papillomavirus (HPV) and high-grade squamous intraepithelial lesions (HSIL) in men can inform anal cancer prevention efforts. We aimed to evaluate the age-specific prevalence of anal HPV, HSIL, and their combination, in men, stratified by HIV status and sexuality. MethodsWe did a systematic review for studies on anal HPV infection in men and a pooled analysis of individuallevel data from eligible studies across four groups: HIV-positive men who have sex with men (MSM), HIV-negative MSM, HIV-positive men who have sex with women (MSW), and HIV-negative MSW. Studies were required to inform on type-specific HPV infection (at least HPV16), detected by use of a PCR-based test from anal swabs, HIV status, sexuality (MSM, including those who have sex with men only or also with women, or MSW), and age. Authors of eligible studies with a sample size of 200 participants or more were invited to share deidentified individual-level data on the above four variables. Authors of studies including 40 or more HIV-positive MSW or 40 or more men from Africa (irrespective of HIV status and sexuality) were also invited to share these data. Pooled estimates of anal high-risk HPV (HR-HPV, including HPV16,

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Section: Hra For All Participantsmentioning

confidence: 99%

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

et al. 2021

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“…Human papillomavirus detection and typing have been described previously 20 . In brief, HPV DNA was extracted using the QIAamp MinElute Media Kit (Qiagen, Valencia, CA) while blinded to participant characteristics.…”

Section: Methodsmentioning

confidence: 99%

Evaluating the Jaccard Similarity Index as a Persistence Measure of Multiple Anal Human Papillomavirus Among Nigerian Men Who Have Sex With Men

et al. 2021

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on behalf of the TRUST/RV368 Study Group Background: Multiple anal human papillomavirus (HPVs) may increase the risk of anal cancer among men who have sex with men (MSM) living with human immunodeficiency virus (HIV). The Jaccard Similarity Index (JSI) was explored as a measure of multiple HPV persistence. Methods:The TRUST/RV368 cohort enrolled MSM living with and without HIV in Abuja and Lagos, Nigeria. Participants with anal swabs at baseline, 3-and 12-month visits were tested for high-and low-risk HPVs using a next-generation sequencing assay. Persistence of the same HPV genotypes over time was calculated using the JSI and categorized into high, medium, and low similarity tertiles. Factors associated with higher versus lower similarity were estimated with multivariable ordinal logistic regression and re-The TRUST/RV368 Study Group is constituted as follows: principal investigators: Manhattan Charurat (IHV

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“…39,40 The study also identified a substantial need for diagnosis and management of other sexually transmitted infections, and new prevention interventions. [40][41][42][43][44][45][46][47] Study findings have subsequently been incorporated directly into prevention and clinical service approaches at the community centers.…”

Section: Rv516mentioning

confidence: 99%

Attaining 95-95-95 through Implementation Science: 15 Years of Insights and Best Practices from the Walter Reed Army Institute of Research’s Implementation of the U.S. President’s Emergency Plan for AIDS Relief

Lee

Ganesan

Khamadi

et al. 2021

The American Journal of Tropical Medicine and Hygiene

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The Walter Reed Army Institute of Research (WRAIR) supports more than 350,000 people on lifesaving HIV treatment in Kenya, Nigeria, Tanzania, and Uganda through funding from the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). Here, we review and synthesize the range of impacts WRAIR’s implementation science portfolio has had on PEPFAR service delivery for military and civilian populations since 2003. We also explore how investments in implementation science create institutional synergies within the U.S. Department of Defense, contributing to broad global health engagements and improving health outcomes for populations served. Finally, we discuss WRAIR’s contributions to PEPFAR priorities through use of data to drive and improve programming in real time in the era of HIV epidemic control and public health messaging that includes prevention, the 95-95-95 goals, and comorbidities.

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Multiple HPV infections among men who have sex with men engaged in anal cancer screening in Abuja, Nigeria

Cited by 12 publications

References 45 publications

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

Evaluating the Jaccard Similarity Index as a Persistence Measure of Multiple Anal Human Papillomavirus Among Nigerian Men Who Have Sex With Men

Attaining 95-95-95 through Implementation Science: 15 Years of Insights and Best Practices from the Walter Reed Army Institute of Research’s Implementation of the U.S. President’s Emergency Plan for AIDS Relief

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