Multiple Familial Angiolipomatosis: Treatment of Liposuction

Kanter, William R.; Wolfort, Frances G.

doi:10.1097/00000637-198803000-00018

Cited by 32 publications

(20 citation statements)

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“…Familial Multiple Lipomatosis [1][2][3][4][5][6][7][8][9][10] Familial multiple lipomatosis (FML) is a predominantly autosomal dominant hereditary syndrome that usually presents with multiple, discrete, encapsulated lipomas found on the trunk, extremities, and occasionally in the neck and shoulders [1]. FML is a very rare disease with a reported incidence of 0.002 % and an increased prevalence in men, which was confirmed by our review (76 % male).…”

Section: Discussionmentioning

confidence: 99%

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Syndromic Lipomatosis of the Head and Neck: A Review of the Literature

et al. 2015

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This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

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Section: Discussionmentioning

confidence: 99%

“…2b) because these patients often present late, and total excision may be difficult and recurrence likely. Liposuction-assisted surgical excision has been described for extremely minor cases [8,9]. However based on our experience, the optimal technique to treat lipomatosis is aggressive surgical excision.…”

Section: Discussionmentioning

confidence: 99%

Syndromic Lipomatosis of the Head and Neck: A Review of the Literature

et al. 2015

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“…reported that males were more affected than females with a ratio of 4 : 1, but Lin and Lin 1 reported equal frequencies among the sexes. Familial angiolipomatosis is not uncommon 5,7–9 …”

Section: Discussionmentioning

confidence: 99%

Multiple subcutaneous angiolipomas associated with new‐onset diabetes mellitus

2002

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A 44‐year‐old Hispanic man, with a past medical history of diabetes mellitus type 2 and cerebrovascular accident, presented to the Mount Sinai Department of Dermatology with sudden, fast‐growing nodules over both of his shins. Approximately 2 months before the appearance of the nodules, the patient was diagnosed with diabetes mellitus type 2 with hemoglobin A1c (HbA1c) of 8.5%. The patient was taking metformin orally, 500 mg three times daily, at the time of presentation. Six nodules appeared over a period of days. They caused a burning, throbbing pain upon ambulation. Over a period of 6 months, the lumps decreased in size, and two totally disappeared. The resolution of the nodules coincided with the control of the patient's diabetes, as demonstrated by HbA1c of 5.5%. The patient denied trauma to the sites of the nodules. The patient denied any associated purpura or ecchymoses over the nodules. The past medical history was significant for a stroke with residual right hemiparesis at 42 years of age. The family history was negative for similar lesions, but an aunt did have diabetes mellitus type 2. The patient denied alcohol use, smoking, or intravenous drug use. Physical examination was positive for six soft, tender, freely mobile, symmetrical, well‐demarcated, round masses, 1–2 cm in diameter and skin colored, over the anterior aspects of both legs. The patient was obese (body mass index, 38.5). Laboratory tests (barring the initially elevated HbA1c) were normal. One lesion was excised. Histopathology revealed features typical of an angiolipoma (see Fig. 1a,b). A karyotype of the angiolipoma was not performed. 1 (a) Prominent vessels filled with fibrin thrombi at the periphery of mature fat lobules. (b) At higher magnification Because excision of one angiolipoma produced scarring with a poor cosmetic result, intralesional triamcinolone, 5 mg/mL, was tried without success.

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“…To a lesser extent, it has been used for reconstructive surgery, for example, in the treatment of lymphedema, 11,30 problems of leakage around colostomies and urostomies caused by bulging fatty skin folds, 34,35 "insulin tumors" caused by the injection of insulin into the subcutaneous fat, 36 multiple familial angiolipomatosis, 37 gynecomastia, 38 and benign symmetrical lipomatosis. 39 Initially, liposuction was done as a "dry" technique, no dilute adrenaline or anesthetics being injected into the adipose tissue beforehand.…”

Section: Liposuctionmentioning

confidence: 99%

From Lymph to Fat

Brorson

2012

The International Journal of Lower Extremity Wounds

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There is some controversy regarding liposuction for late-stage lymphedemas. Although it is clear that conservative therapies such as complex decongestive therapy and controlled compression therapy should be tried in the first instance, options for the treatment of late-stage lymphedema that is not responding to treatment is not so clear. Liposuction has been used for many years to treat lipodystrophy. Some results have been far from optimal; however, improvements in technique, patient preparation, and patient follow-up have led to a greater and a wider acceptance of liposuction as a treatment for lymphedema. This article outlines the benefits of using liposuction and presents the evidence to support its use.

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Multiple Familial Angiolipomatosis: Treatment of Liposuction

Cited by 32 publications

References 0 publications

Syndromic Lipomatosis of the Head and Neck: A Review of the Literature

Syndromic Lipomatosis of the Head and Neck: A Review of the Literature

Multiple subcutaneous angiolipomas associated with new‐onset diabetes mellitus

From Lymph to Fat

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