Multiple discharging sinuses: An unusual presentation caused by <i>Absidia corymbifera </i>

Abstract

A case of zygomycosis presenting with non-healing multiple discharging sinuses in a diabetic patient is reported here. The debrided tissue on histopathological examination revealed dense inÞ ltration with aseptate fungal hyphae. Potassium hydroxide mount showed hyaline aseptate hyphae suggestive of zygomycosis. On culture, Absidia corymbifera was isolated. The patient responded to surgical debridement and therapy with amphotericin B followed by itraconazole.

Palatal zygomycosis: experience of 21 cases

“…and, to a lesser extent, other species may be isolated, like Mucor, Absidia, Cunninghamella, Rhizomucor and Apophysomyces, among others (Roden et al , 2005). The major causative agent in our report was R. oryzae , which coincides with other series (Hauman and Raubenheimer, 1989; Van Der Westhuijzen et al , 1989; Jones et al , 1993; Damante and Fleury, 1998; Kyrmizakis et al , 2002; Pandey et al , 2004; Tugsel et al , 2004; Huang et al , 2005; Roden et al , 2005; Jayachandran and Krithika, 2006; Kindo et al , 2007). It is important to emphasize that the virulence of strains is difficult to evaluate, but differences have indeed been reported ( in vitro ) in the susceptibility of fungi to various antifungals.…”

A case of otomycosis caused by Lichtheimia corymbifera (syn. Absidia corymbifera, Mycocladus corymbifer) in a healthy immunocompetent individual

“…A. corymbifera is a relatively rare case of human zygomycosis. [7] Although infection with A. corymbifera usually occurs in immunosuppressed individuals, Absidia infections in immunocompetent hosts have also been described. [8][9][10] case report A 55-year-old male presented to our ENT OPD with history of left-sided earache and ear discharge since 10 days.…”