Multiple complications in a dog infected with <i>Babesia gibsoni</i>

Almendros, Angel; Burchell, Richard K.

doi:10.1002/vrc2.126

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…However, to the best of the authors’ knowledge, clinicopathological features associated with this infection in cats have not yet been described. Clinical and laboratory findings in this case were similar to those described for babesiosis due to B. gibsoni infection in dogs [ 7 , 22 ]. Pseudothrombocytopenia in vitro in cats is possible and needs to be differentiated when severe low platelet count is present.…”

Section: Discussionsupporting

confidence: 81%

“…Although there is no definitive evidence of the regional tick vector species, Muguiro et al (2023) postulate that Rhipicephalus sanguineus sensu lato and Haemaophysalis longicornis ticks are likely vectors. Infected dogs are frequently asymptomatic, and the diagnosis of babesia infection is serendipitous [ 7 ]. The main clinical findings in dogs with babesiosis are regenerative haemolytic anaemia and thrombocytopenia [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

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Babesia gibsoni Infection in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia

Almendros

Choi

Bęczkowski

et al. 2023

Animals

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Tick-borne haemoparasite Babesia gibsoni has been detected rarely in cats, in surveys of apparently healthy animals. In stored blood from a 6-year-old male-neutered domestic shorthair cat in Hong Kong, B. gibsoni DNA was detected retrospectively using PCR for Babesia spp. 18S rRNA and mitochondrial cytochrome B genes, followed by sequencing and basic local alignment search tool (BLAST) analysis. The cat presented with severe haemolytic anaemia and thrombocytopaenia. The cat responded to supportive care and glucocorticoids and was clinically normal despite persistent subclinical thrombocytopenia until six months after presentation, when it succumbed to a fatal haemorrhagic episode. Necropsy revealed severe intestinal and pulmonary haemorrhage and hypocellular bone marrow with megakaryocytosis but no other causes of immune-mediated thrombocytopaenia (IMTP) or immune-mediated haemolytic anaemia (IMHA). Blood stored on days 158 and 180 tested PCR negative for Babesia spp. This report demonstrates that geographic range of B. gibsoni detection in cats includes Hong Kong. The exclusion of other causes suggests that B. gibsoni might have potentially played a role in triggering immune-mediated disease in this case.

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Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Babesia gibsoni Infection in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia

Almendros

Choi

Bęczkowski

et al. 2023

Animals

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Low prevalence of Babesia hongkongensis infection in community and privately-owned cats in Hong Kong

Almendros,

Choi,

Leung

et al. 2024

Ticks and Tick-borne Diseases

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The effect of transfusion of erythrocyte mass on clinical and haematological indicators of dogs with hemolytic anaemia caused by babesiosis

Maliuk,

Kulida,

Klymchuk

et al. 2023

Ukrainian journal of veterinary sciences

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The relevance of the research is due to the spread of protozoal diseases of animals, which, in the absence of the necessary veterinary care, lead to death. In this regard, the aim of the study was to investigate changes in clinical and haematological parameters in dogs under complex treatment of babesiosis with simultaneous red blood cell transfusion. Transfusions were performed in five animals infected with Babesia canis by intravenous injection of red blood cells, the volume of which was calculated using the Sackmen formula. The diagnosis of babesiosis was made based on anamnesis, clinical symptoms (weakness, refusal to food, pallor of visible mucous membranes, fever up to 40°C), and confirmed by microscopic detection of babesiae in blood smears. Before transfusion, rapid tests were performed to exclude heartworm disease in donor dogs. The compatibility of the blood of the donor and recipient animal was determined using a large cross-test. The condition of the abdominal organs of the patients was assessed using ultrasound diagnostics. Clinical examination of the dogs’ blood before treatment indicated the development of anaemia. The results of biochemical blood tests indicated an increase in the activity of alanine aminotransferase and gamma-glutamyl transpeptidase, which indicates a load on the hepatobiliary system. There were no contraindications to blood transfusion. After haemotransfusion, the clinical condition of the dogs was monitored based on the results of the examination of the animals, taking into account the anamnesis and haematological studies on the second, fifth, and tenth days of treatment. During the second and fifth days, a gradual increase in blood haemoglobin content and haematocrit value was noted. On the tenth day, there was a significant positive trend in the number of red blood cells, haemoglobin content and haematocrit to the reference values. It was established that the use of red blood cell transfusion in dogs with babesiosis as part of therapy contributed to the fastest recovery of the general condition of the animal. The material of the article is of practical value for the use of red blood cell transfusion in the treatment of dogs with babesiosis

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Multiple complications in a dog infected with Babesia gibsoni

Cited by 3 publications

References 27 publications

Babesia gibsoni Infection in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia

Babesia gibsoni Infection in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia

Low prevalence of Babesia hongkongensis infection in community and privately-owned cats in Hong Kong

The effect of transfusion of erythrocyte mass on clinical and haematological indicators of dogs with hemolytic anaemia caused by babesiosis

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